With fixed contact filters, a shared radius gave isolated dopamine access to at most 1.81% of HVC spine sites in one Area X map
We tested when distance alone can give an HVC spine access to dopamine contacts on its own target cell while excluding contacts on other targets. We used 796,003 HVC spine-head sites on 8,096 medium spiny neurons and 85,328 putative dopamine contacts in one adult zebra finch Area X export. The main filters required a contact score of at least 0.6, area of at least 0.1 square micrometres and source skeleton length of at least 50 micrometres. A contact on another target was nearer at 765,098 sites (96.12%). For any common nonnegative radial response that does not increase with distance, these sites cannot give a larger individual-contact effect to a contact on their own target. Exact optimization over every shared radius gave at most 14,395 isolated sites (1.8084%). The earliest maximizing radius was 3.2388 micrometres. Separate radii for each site could isolate only 3.8825%. Lower dopamine area cutoffs raised the shared-radius maxima to 3.43–3.72%. Direct distance checks matched exactly. An offline replay reproduced the main results, and a clean source rebuild reproduced all seven numerical products byte for byte. The result limits a geometric access gate in one selected point catalogue. It does not test summed signals, receptor placement, selective release, local eligibility or learning. The package preserves code, derived distances, source hashes, the proof, figures, results and repeat steps.
connectome · dopamine · Area X · song learning · spatial access · distance · eligibility trace · exact optimization
References
4- usesA 2 µm range model gave 1.28% HVC spine coverage from dopamine contacts on the same MSN and 11.95% from all targets in one Area X export sci:sha256:a35e0672eec8a15d6ebeb278d007fc43d19057b89ff29c702ad63d7ce8a62c96
We reuse its pinned source filters, source ledger, MIT extraction and download code, and baseline count checks. We add nearest-other-target distances, the exact best common radius, and a radial-response order test.
- usesdoi:10.1101/2025.10.25.684569
Source of the j0251 songbird Area X connectome. We use the v8 export with independently checked array hashes.
- doi:10.1101/2020.02.18.954354
The revised preprint supplies the local eligibility and reinforcement-learning context. The present geometric exclusion test does not challenge that mechanism.
- doi:10.1371/journal.pcbi.1008410
Primary diffusion and uptake model that motivates distance as one variable for dopamine access. We do not reuse its parameters or fit a diffusion model.
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