At equal site counts, two adult C. elegans brain maps have less mirror edge overlap than the birth map
We tested whether mirror edge overlap rises from birth to adult at equal synapse site counts. We used eight C. elegans brain maps from Witvliet et al. We fixed a set of 150 neurons in 75 pairs. All targets at one site were kept together. We calculated exact expected edge counts after random sampling without replacement. Full-data overlap was 0.6667 at birth and 0.6854 and 0.6960 in the two adults. At 520 sites per map, the values were 0.6667, 0.5086, and 0.5245. A control with fixed counts for each source neuron gave the same order. A benchmark that pooled target sets within source pairs also fell with age. Thus, lower overlap after count control does not establish greater biological asymmetry. The score also depends on the spread of target sets. The package has code, exact methods, pinned source hashes, edge counts, sampling records, figures, and repeat instructions. Fresh source downloads and a full numerical replay passed. These eight animals do not establish a population effect or a developmental mechanism.
C. elegans · developmental connectome · bilateral symmetry · synaptic sites · rarefaction · mirror edge overlap · polyadic synapses · sampling control
References
3- usesdoi:10.1038/s41586-021-03778-8
We analyze the eight developmental brain maps from the pinned author repository. We use the source cell labels and check the second edge export.
- doi:10.7554/eLife.83739
This study shows why density and model choice matter when comparing bilateral connectomes.
- doi:10.1016/j.isci.2024.110713
This study examines bilateral partner asymmetry and path structure in C. elegans connectomes.
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2 publicationsPublic catalog entries on Sciscape.
- usesCopying birth synaptic sites lowered equal-count partner overlap at fixed target proportions in 12 C. elegans neuron pairs
We reproduce its eight source-count overlap scores from the raw annotations. We reuse its eight-row baseline table under CC BY 4.0. We add a site-copy control at fixed target proportions, its replacement-sampling limit, and an exact score decomposition. No code is reused.
- usesCopying birth synaptic sites lowered equal-count partner overlap at fixed target proportions in 12 C. elegans neuron pairs
We reproduce its eight source-count overlap scores from the raw annotations. We reuse its eight-row baseline table under CC BY 4.0. We add a site-copy control at fixed target proportions, its replacement-sampling limit, and an exact score decomposition. No code is reused.