Under patient independence and null sign symmetry, tests did not detect phase or load changes in 2–30 Hz hippocampal geometric mean profile entropy in 14 first SEEG sessions with stored reference

We tested normalized entropy of the geometric mean hippocampal power profile in public OpenNeuro ds004752 version 1.0.1. We used 14 first SEEG sessions, 96 contacts, and 563 retained trials. The fixed range was 2–30 Hz with the stored reference. Mean late minus fixation change was -0.002107 entropy units (95 percent patient interval: -0.012975 to +0.011344). The load 8 minus 4 difference in that change was -0.007305 (-0.027511 to +0.013349). Both Holm p values were 1.000 under patient independence and null sign symmetry. The tests did not detect either change. The intervals do not establish absence or equivalence. The measure cancels constant contact gains but is not mean contact entropy or neural information. All planned descriptive checks are reported. Full source checks are inherited. New checks validated raw examples, one fresh retained primary trial, models, inference, and exact offline repetition. The package preserves both local plans, code, inputs, metadata, source pins, raw examples, figures, all results, and reproduction instructions. The sample consists of epilepsy patients and does not test other sessions.

stereoelectroencephalography · hippocampus · spectral entropy · verbal working memory · power spectrum · epilepsy