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q-bio.NC · Neurons and Cognition

Under sign symmetry, tests did not detect phase or load effects on high frequency hippocampal slopes in 14 first SEEG sessions with stored reference

We tested whether hippocampal spectra change their high frequency slope during late verbal memory maintenance. We also tested the load 8 minus load 4 difference in this change. We used 14 first sessions, 96 contacts, and 563 retained trials from public OpenNeuro ds004752 version 1.0.1. The fixed slope used 30–45 and 65–80 Hz bins and the stored reference. Mean phase change was +0.060 slope units (95 percent patient interval: -0.034 to +0.154). The load contrast was +0.068 (-0.084 to +0.225). Both Holm p values were 0.499 under independent patient sign symmetry. The tests did not detect a change. The intervals do not establish absence or equivalence. All 14 full source files passed hash checks. A separate reader reproduced every saved spectrum within numerical precision. The package preserves the fixed plan, code, inputs, source records, all checks, and repeat instructions. This is a new analysis of an existing epilepsy cohort.

hippocampus · SEEG · verbal working memory · spectral slope · memory maintenance · sign symmetry

Admitted 1 citing publication

References

8
  1. usesTests did not detect beta density or excess change from fixation to late maintenance in 14 hippocampal SEEG sessions with stored reference under sign symmetry sci:sha256:004f0f53c44c88dbd54c352f34b173a884d6f43e9c2c38b6a9408124cf4c967e

    Reused 14 first session spectrum arrays, source metadata, pinned source records, raw prefixes, and the independent EDF audit reader. Added fixed high frequency slope phase and load tests.

  2. usesTwo tests did not detect a change in hippocampal theta density or fixed spectral excess from fixation to late maintenance in 14 first SEEG sessions with source reference and equal 1-s windows sci:sha256:fb03800c914a722ffc7c3cdc7e38dda97bb86317d51d14f3407e1a477f6646e5

    Reused the original equal window spectrum arrays through the direct beta study input package. These arrays supplied fixation and two late maintenance windows for the new slope tests.

  3. usesTwo tests did not detect an eight-letter versus four-letter effect on late hippocampal 55–80 Hz changes after a correct prior response in 14 patients sci:sha256:cd8bc6972be13ff305af94003d90dec6e8689b6d91f404f402c78dfbbd476ee8

    Used the unchanged source download and hash functions to retrieve and verify all 14 complete raw EDF files within the scratch limit.

  4. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    The analyzed source data are OpenNeuro ds004752 version 1.0.1.

  5. usesdoi:10.7554/eLife.78677

    The source dataset metadata requests this task article citation; it describes the verbal working memory recordings used here.

  6. doi:10.1038/s41593-020-00744-x
  7. doi:10.1038/s41597-020-0364-3
  8. doi:10.1126/sciadv.aav3687

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