Midpoint times lowered the mean MNI HFO order score at 25 ms in 18 SEEG sleep records with fixed onset directions

We checked the effect of event time choice on high frequency oscillation (HFO) order in 18 public SEEG sleep records. We fitted contact-pair directions from MNI detector starts in the first half-hour. We kept those pairs and directions for the second half-hour. At a 25 ms window, the mean score was 0.008790 for starts and 0.002311 for interval midpoints. The paired mean difference was -0.006479. Its 95% patient resampling interval was [-0.015886, -0.000653]. The exact patient sign-flip test gave p = 0.01231, under symmetric null signs. The score fell in 13 of 18 records. Intervals overlapped or touched in 72.1% of fixed onset matches, with equal weight per patient. This audit uses the earlier onset study cohort. It does not establish neural propagation. The package preserves source bytes, code, results, figures, and offline checks.

high frequency oscillations · SEEG · event timing · interval midpoint · measurement sensitivity · neuroscience

Admitted 2026-11-09 19:58 UTC1 citing publication

References

usesTransitive 50 ms grouping of released STE marks gave incompatible shaft sets in the first hour of 13 of 18 SEEG sleep records sci:sha256:9b0ac923e9441d51f29833d882af4069d93a5c6db95a7fa2f51902268d15b520
We used the compressed public source archive, fixed source manifest, and retrieval code. All 94 pinned public source files or EDF headers passed fresh byte and hash checks.
usesReleased MNI HFO onset order repeated on average between half-hour periods in 18 UCLA SEEG sleep records sci:sha256:e0cfbb49c59f29623e27f8b20f783a76506e6c73efa6ed8e26d20730aa6a87f4
We used the onset score, source parser, interval join, circular counter, code notice, and earlier patient results. All 18 primary onset patient scores matched exactly. The new audit kept the same pairs and fitted onset directions while it changed the test event time.
usesdoi:10.18112/openneuro.ds005398.v1.1.3
Source event tables and metadata from OpenNeuro ds005398 v1.1.3 were used; the analysis used archived files from the fixed source commit recorded in the README.

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usesIndependent 0.5 ms endpoint limits preserved the mean STE SOZ occupancy AUC lead over MNI within shafts in 17 first-hour SEEG sleep records
The prior onset versus midpoint audit informed the timing sensitivity question. The present study tests SOZ ranks under endpoint limits, with fixed marks and channel pairs.