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q-bio.NC · Neurons and Cognition

SEEG shape difference estimates stayed positive at 1 and 2 mA in three people at 20 to 500 ms with an independent pulse noise model

We tested a shape measurement for brain stimulation calibration. Public STReEF SEEG data supplied 54 matched conditions from three people. Each condition had five pulses at 1 mA and five at 2 mA. The main window was 20 to 500 ms. Products of different pulses estimated a determinant, which measures waveform shape difference. A proof gives an unbiased unscaled estimate for fixed mean responses and independent pulse errors with mean zero. After aggregation, the shape ratios were 0.489, 0.232, and 0.716. Ratios from five-pulse means were 0.616, 0.250, and 0.621. The equal-person mean changed from 0.496 to 0.479. The ratio itself has no unbiasedness claim. Before-pulse normalization was unstable. Shared pulse noise gave a positive estimate for proportional signals in a simulation. Current and time changed together. These results do not establish a causal current effect or a population difference. The package preserves the proof, code, exact inputs, source pins, results, three figures, and repeat instructions. All 540 fresh source ranges matched. All 147 fresh metadata files matched. Seven analysis files repeated exactly.

SEEG · stereo-electroencephalography · pulse noise · waveform shape · Gram determinant · brain-computer interface

Admitted 1 citing publication

References

7
  1. usesDoubling 1 mA templates increased 2 mA forecast error after mean removal in three SEEG participants at 20 to 500 ms sci:sha256:ed5d2e82c3ea575a465a18d21828edcfd06200c1c68665190148aa4c4428e7ca

    This work supplied the metadata selection and source range extraction code inherited through the input publication. We preserve the code, source pins, and credit. The new fourth-order estimator uses its fixed matched-current SEEG cohort.

  2. supersedesSEEG shape difference estimates stayed positive at 1 and 2 mA in three people at 20 to 500 ms with an independent pulse noise model sci:sha256:a83bc243f3f1c638d09de987ea902f7b5be84c5b07b2d57aa08157c65c7ff5c5

    This version corrects the local package hash check. It ignores the supplemental metadata folder that sci adds on retrieval. The proof, source data, estimates, and figures are unchanged.

  3. usesThe pulse variation term was 90.5% of normalized extra error from doubled SEEG templates in three people at 20–500 ms sci:sha256:79c438b01112cf67e4a85c8f25639a32b117622a1ece3e17c9e494be9efd54a1

    This prior analysis separated pulse variation from a doubled-template forecast comparison in the same public cohort. We use it as context for a separate shape measurement. We inspected its record after our first primary estimates. Our target is a fourth-order Gram determinant, not its forecast contrast.

  4. usesSeparate scales along and outside a 1 mA waveform increased mean 2 mA SEEG forecast error after mean removal at 20 to 500 ms in three participants sci:sha256:de62aec0d59c8930643cc515ebb538cebd3d6436822605710ade23f933cd51c2

    This work supplied the exact 54-condition cohort, pulse Gram matrices, audit epochs, pinned source ranges, and source metadata. We used these inputs to estimate a waveform determinant rather than forecast error. We rebuilt all 540 selected ranges and checked all arrays against the public source objects.

  5. usesdoi:10.18112/openneuro.ds005448.v1.0.0

    The analyzed recordings and fixed cohort are from STReEF, OpenNeuro ds005448 version 1.0.0.

  6. doi:10.1016/j.ynirp.2025.100274
  7. doi:10.1007/s12021-022-09567-6

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