Peak times from four pulse means agreed within 5 ms more often after limbic stimulation than before it in seven tested SEEG groups under fixed source correction

We tested early peak time repeatability in one public SEEG stimulation group from each of seven patients. Two pulses selected contacts with large waveform energy. Two separate four pulse means gave timing estimates. Agreement within 5 ms was 79.56 percent after stimulation and 12.95 percent before it. The mean increase was 66.61 percentage points. Its conditional 95 percent patient bootstrap interval was 48.53 to 81.96 points. The exact two sided patient sign flip probability was 0.015625. All seven patients had an increase. The test used 137 contacts and all 1,575 partitions per group. Four planned checks retained the increase. Exact voltage windows, code, source records, results, and reproduction instructions are preserved. The source correction used all exported trials and stayed fixed. Only seven source-order groups were tested. The result measures timing repeatability after that correction; it does not measure neural conduction delay.

SEEG · electrical stimulation · peak time · repeatability · evoked potentials · limbic system · pulse partitions · patient bootstrap