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Average and Cz references gave opposite estimated C3/C4 squared imaginary beta coherency contrast signs in 3 of 6 accepted ds002778 pairs

We tested C3/C4 beta scores in Parkinson medication pairs from OpenNeuro ds002778 version 1.0.5. The main test used a squared imaginary coherency score from 13 through 30 Hz. Both reference rules used the same accepted EEG windows. The fixed artifact rule retained 6 of 13 pairs with raw-source sessions. Average and Cz references gave opposite estimated contrast signs in 3 pairs. The mean reference difference was 0.000958 [-0.003103, 0.005826]; brackets give the 95% participant bootstrap interval. The exact sign-flip test gave p = 0.71875. The test did not resolve a mean shift. The package preserves all planned checks, window Fourier values, source hashes, code, and a source retrieval recipe. The small accepted sample and remaining artifacts limit interpretation. These scores do not establish a medication effect or a direct brain connection.

electroencephalography · EEG reference · coherency · Parkinson disease · beta band · signal processing · reproducibility

Admitted 5 citing publications

References

8
  1. usesdoi:10.18112/openneuro.ds002778.v1.0.5

    Source EEG metadata and files for OpenNeuro ds002778 version 1.0.5.

  2. doi:10.1016/j.nicl.2013.07.013
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    Documents reference choice effects on scalp EEG connectivity estimation.

  4. supportsdoi:10.1016/j.clinph.2004.04.029

    Supports the stated role of the imaginary coherency component in reducing false coupling from instantaneous source mixing.

  5. doi:10.1523/ENEURO.0151-19.2019
  6. doi:10.1002/ana.24507
  7. doi:10.21105/joss.01896
  8. doi:10.1038/s41597-019-0104-8

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