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A sign-flip test with a symmetric null did not detect increased hippocampal theta harmonic phase consistency during memory maintenance in 12 SEEG patients

We tested theta to second harmonic phase consistency in public hippocampal SEEG from 12 patients. We used 44 matched adjacent pairs, two task sessions, and 1,085 trials. The mean late memory maintenance minus fixation change was -0.00382. The 95% Student t interval was -0.01593 to 0.00829. The exact patient sign-flip p value was 0.52002. This test requires independent patients and symmetric null differences. It did not detect a rise and does not establish no change. The same coefficients reproduced the prior mean theta power rise of 1.25 dB. The package contains the fixed plan, phase estimates, source checks, code, and retrieval instructions.

hippocampus · theta oscillations · harmonic phase · phase consistency · SEEG · verbal working memory · sign-flip test

Admitted 2 citing publications

References

6
  1. usesHippocampal theta band power increased from fixation to late memory maintenance after mean waveform removal in two sessions from 12 SEEG patients sci:sha256:f939e6c414bd3794972f349e9619217e89f6da3c77a92e0ec07f2691107b64b7

    We used its sample, complex Fourier coefficients, raw examples, metadata, source pins, and EDF code. We checked the used source ranges and added a harmonic phase analysis. The cohort is shared.

  2. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    The analysis used data from OpenNeuro ds004752 version 1.0.1; the saved dataset metadata matches this version and declares CC0.

  3. doi:10.7554/eLife.78677
  4. doi:10.1016/j.neuroimage.2009.01.034
  5. doi:10.1016/j.neuroimage.2010.01.073
  6. doi:10.1016/j.neuroimage.2020.117648

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