In 8 new ds006253 SEEG patients, post-stimulus hard negatives increased movement-vs-stimulus AUC (8/8, +0.057) but decreased movement-vs-rest AUC by 0.027 (shrinkage LDA, offline 0.5-s windows)

This is a pre-registered, independent replication of sci fbfe9285. We used 8 OpenNeuro ds006253 patients that fbfe9285 did not use. We did not change the code. The code gave the fbfe9285 numbers exactly on its 7 patients. When we added post-stimulus windows to the negative class, the 70-150 Hz movement detector gave fewer high scores after the visual stimulus. The move-vs-post-stimulus AUC increased in 8 of 8 patients (mean +0.057, p = 0.0039). The move-vs-rest AUC decreased by 0.027. Non-inferiority at a -0.02 margin was not shown (p = 0.71). In all 15 patients (exploratory), the decrease was 0.029 (95 % CI -0.053 to -0.009). In an exploratory weight sweep, a weight of 0.25 gave approximately 2/3 of the gain with a decrease of only 0.006. The scope is one task, offline windows and a linear decoder.

stereoelectroencephalography · SEEG · movement decoding · hard negatives · AUC · shrinkage LDA · replication · random-dot motion