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Stored and bipolar signals gave opposite theta coupling change estimates in 4 of 8 valid public SEEG sessions

We tested whether theta coupling changes depend on the reference and time segment in OpenNeuro ds006065 version 1.0.0. The data contain nine stimulation sessions from seven people with epilepsy. Eight sessions from six people passed the primary quality rule. We used 80 seconds before and after stimulation and three signal references. The primary measure was debiased squared weighted phase lag index at 4 to 8 Hz. Stored and bipolar signals gave opposite change signs in 4 of 8 valid sessions. Stored and mean SEEG signals gave opposite signs in 0 of 8 sessions. Across two non-overlapping 40-second samples, signs matched in 6 of 7 bipolar comparisons and 1 of 7 stored-reference comparisons. 24 of 24 primary sampling intervals included zero. These are estimates from short recordings. They do not establish a causal stimulation effect or show that one reference is correct. The package preserves derived signal data, source versions and hashes, fixed analysis rules, code, tables, figures, and independent estimator checks.

stereoelectroencephalography · theta coupling · phase lag index · weighted phase lag index · signal reference · time sample · intracranial EEG · stimulation

Admitted 5 citing publications

References

2
  1. usesdoi:10.18112/openneuro.ds006065.v1.0.0

    The analysis used the named rest recordings from OpenNeuro ds006065 version 1.0.0.

  2. usesdoi:10.5281/zenodo.14735080

    The study used the author code record to identify phase and stimulation contacts; its GPL-licensed archive is linked externally.

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