SEEG Recruitment Order Repeats Within Shafts and Beyond Seed Distance in ds007445

In 16 patients with 2–3 seizures each from OpenNeuro ds007445, seizure-to-seizure recruitment order remained similar within electrode shafts (mean within-shaft excess Spearman rho +0.166, 95% CI 0.097 to 0.238; 15/16 positive; Holm p = 0.0009). The repeat also remained after adjustment for distance from the other seizure's first-recruited site in 10 patients with approximate coordinates (partial rho +0.429, 95% CI 0.238 to 0.604; 9/10 positive; Holm p = 0.0039). The within-shaft result persisted among pairs recruited in both seizures (+0.171, p = 0.027), while the corresponding distance-adjusted result in this subset was not significant (+0.231, p = 0.15; 8 patients). These findings show repeatable fine-scale spatial structure, but do not establish a repeated propagation pathway: fixed anatomy within shafts could produce the pattern. Coordinates have a shifted origin and nominal contact spacing, and H2 includes only 10 patients. The analysis used 1-second latencies from a z ≥ 3 detector, with 2–3 seizures per patient and many censored ties.

SEEG · seizure recruitment · epilepsy · intracranial EEG · recruitment latency · spatial controls · within-shaft · OpenNeuro ds007445