Exclusion of 55 to 65 Hz changed gamma onset AUC by at least 0.05 in 14 of 35 SEEG patients when higher power was the onset score
We tested a fixed gamma power score in public SEEG from OpenNeuro ds004100, version 1.1.3. Each of 35 patients had two 60-second interictal excerpts. The cohort had 4,149 retained contacts. Higher absolute power was the fixed score for a clinical seizure onset contact. Exclusion of 55 to 65 Hz from the 30 to 80 Hz sum changed patient AUC by at least 0.05 in 14 patients. Changes ranged from -0.238 to +0.405. The median paired change was +0.0195. Its 95 percent patient bootstrap interval was 0.0000 to +0.0625. The exact two-sided sign test gave p = 0.0801433. This did not meet the fixed p < 0.05 threshold. The primary test did not establish a consistent improvement. All 72 source excerpts passed fresh MNE and SciPy spectrum checks. The package preserves input spectra, code, source metadata, scores, patient results, bootstrap draws, hashes, and retrieval instructions. The interval removes biological bandwidth as well as possible electrical noise. The result concerns this reused cohort and these short files. It does not show clinical benefit or a general noise removal rule.
stereoelectroencephalography · SEEG · epilepsy · gamma power · spectral power · seizure onset zone · AUC · contact ranking · 60 Hz · frequency bands · Welch spectrum · OpenNeuro
References
5- usesCommon average reference raises median relative gamma rank agreement in two 60 s SEEG records from each of 36 HUP patients sci:sha256:3f5f9f6ae779730a7bf70359ae9ddc56a5032c2e8abdb97c0cf3c127d6082e74
We used all 36 preserved patient spectra, source metadata, contact selection, and pinned retrieval code. These inputs enabled the new frequency interval comparison. We checked all 72 raw excerpts with MNE and SciPy.
- usesDivision by total power lowered gamma AUROC in paired 60-second SEEG samples from 35 patients when higher scores marked seizure onset contacts sci:sha256:c83c25b21f95628d5ea3494c73122433aa202d4dcc652648cb0dd6fec9e495c5
Its comparison of absolute and relative gamma scores informed the new question and fixed higher power score direction. We reused the same 35-patient cohort and onset labels. We tested inclusion and exclusion of 55 to 65 Hz.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
Source SEEG dataset used for the preserved spectra and cohort.
- doi:10.1093/brain%2Fawab480
- doi:10.1016/j.neuroimage.2018.08.020
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