A calibrated late SEEG score gave a 1.02-point mean site accuracy gain with a 95% interval across zero in five sessions

We tested if a late SEEG score helps identify the site of a known stimulation pulse. Public OpenNeuro ds004457 version 1.0.2 supplied five sessions, 183 sites, 15 recording pairs, and 732 test pulses. Four early pulses per site calibrated each reader and selected the late weight. Four later pulses per site tested it. Mean accuracy was 35.85% for 20–100 ms responses and 36.87% for the calibrated early and late score combination. The late window was 100–500 ms. The mean change was +1.02 percentage points. The descriptive 95% patient bootstrap interval was -1.50 to +4.00 points. The exact two-sided patient sign-flip value was p = 0.75. The data did not establish an accuracy gain. This was an offline test within sessions. Global calibration and test time ranges overlapped in every session. The package preserves voltage inputs, figures, code, fitted readers, source hashes, and reproduction instructions. Fresh raw extraction, independent score checks, and repeated analysis matched the saved results.

SEEG · electrical stimulation · site identification · evoked potentials · late responses · covariance cosine · calibration · intracranial EEG

Admitted 2026-11-09 19:32 UTC2 citing publications

References

usesSEEG response shapes at 15–100 ms gave higher site identification accuracy than shapes at 100–500 ms within each of five patient sessions sci:sha256:aa5b71d76d214f861e99964287f9da01f3f9fc6c707a4dcfe24807283918ab40
We used its early and late waveform-reader comparison to choose the question. The current test uses more recording pairs, four calibration pulses per site, and calibrated covariance-score combination.
Absolute pair scores kept SEEG site decisions fixed under simulated output sign reversals in five sessions sci:sha256:8a26582c314b8be03ef05d9206ae910fa50daac8c1ccee11c5df2d7794d6821e
[Legacy relation: reproduces] We reproduced its signed early-reader accuracies exactly: 54/140, 42/196, 62/140, 47/140, and 48/116. This relation covers that baseline, not its absolute-score sign-reversal result.
usesAbsolute pair scores kept SEEG site decisions fixed under simulated output sign reversals in five sessions sci:sha256:8a26582c314b8be03ef05d9206ae910fa50daac8c1ccee11c5df2d7794d6821e
We used its signed pair covariance cosine functions for the early baseline and for the separate late reader. Only the command-line label field lookup was adapted.
usesMean estimated SEEG site map alignment was 0.28 for 20 to 100 ms and 100 to 500 ms in five sessions under stable means and independent group errors sci:sha256:3da61344038cc338985933849b56f820fd6f4dd48b236c6f72c5aa873d6fbe28
We used its fixed five-session voltage inputs, site and pair selection, source manifest, metadata, and extraction and retrieval code. Its early and late site map result informed the new score combination question.
usesdoi:10.18112/openneuro.ds004457.v1.0.2
The five analyzed sessions and voltage inputs came from OpenNeuro ds004457 version 1.0.2; the saved source audit records matching pinned files and snapshot tree.
doi:10.1523/JNEUROSCI.1325-22.2023

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usesAn early SEEG gate had a 2.44-point mean utility gain with a 95% interval across zero at a 0.05 delay cost in five sessions
This package supplied the covariance-cosine reader code and the prior late-score comparison. The new analysis fitted an early decision to wait on a stricter remote-shaft cohort. It did not use the prior test predictions.
usesAn early uncertainty gate gave no clear gain over random waiting for known neighboring sites in five offline 6 mA SEEG sessions
The prior early and late score result informed the time windows and question. This study used conditional waiting for neighboring candidates, rather than a calibrated late-score weight.