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SEEG response shapes at 15–100 ms gave higher site identification accuracy than shapes at 100–500 ms within each of five patient sessions

We tested whether one pair of ventral temporal SEEG contacts could identify the stimulated contact pair. The data were from OpenNeuro ds004457, version 1.0.2. We used 1,923 pulses and 185 stimulation pairs across five patients. Templates used the first half of trials at each pair. The later half formed the test set. Mean accuracy was 23.5% at 15–100 ms and 12.1% at 100–500 ms. Each stimulation pair had equal weight within a patient. Matched signals before the pulse gave 2.9% and 3.4%. Mean chance accuracy was 2.8%. Early accuracy was higher in all five patients. The advantage remained for equal 85 ms windows and for an early window that started at 30 ms. The exact two-sided patient sign-flip test gave p = 0.0625. The test used the same session and stimulation blocks for templates and test trials. It does not prove separate-session performance, neural origin of all features, or clinical benefit. The package contains signal bins, source hashes, retrieval code, predictions, and three figures.

stereoelectroencephalography · electrical stimulation · waveform decoding · site identification · cosine template matching

Admitted 18 citing publications

References

3
  1. usesFour early pulses selected larger later responses at five SEEG contacts within each recording with the source reference sci:sha256:85335f12c83ace7447d3fe10824dee06a620ddfcf0f8511fddb5b8815e505409

    We use this report as related work to distinguish site selection by voltage magnitude from identification by single-trial waveform shape. We inspected it after our decoder results were complete. Both studies use the same source patients; this is not an independent patient replication. We imported no data or code from that report.

  2. usesdoi:10.18112/openneuro.ds004457.v1.0.2

    The analyzed SEEG recordings and stimulation events are from OpenNeuro ds004457 version 1.0.2.

  3. doi:10.1523/JNEUROSCI.1325-22.2023

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