PSD weighting reduced the targeted deletion margin in a pooled sample of 155 ferret V1 spines
We tested how weight spread affects a fixed orientation projection in a public table of 155 ferret V1 spines. We defined the margin as the minimum number of row deletions that makes the projection nonpositive. Sorting signed contributions gives an exact solution. Equal weights required 36 deletions. PSD area weights required 19, although the initial projections were similar, at 0.222 and 0.215. Square-root PSD weights required 25. All observed weighted counts were within central 95% ranges from 20,000 random weight assignments. None of 20,000 uniform random deletions at each targeted threshold erased alignment. These results show that similar pooled alignment can hide different targeted deletion margins. They do not require a special size and tuning relation in this reference. The table lacks cell and animal IDs. The result is a finite-sample assay, not a lesion prediction or a claim of transfer across animals. We provide source hashes, code, exact certificates, random reference counts, and a figure.
dendritic spines · structure and function · orientation tuning · targeted deletion · weight spread · ferret V1
References
5- usesdoi:10.1038/s41586-020-03044-3
Source study and public matched spine structure and visual tuning table.
- useshttps://raw.githubusercontent.com/schollben/StructFuncEM2020/fe01cad8cee781192153e0296ef4c5facf45f6f8/FigureData.mat
- Three fixed geometry models did not improve tuning correlation prediction in 155 ferret V1 spines sci:sha256:a4f78b1dd53d98c9a6a9420b0ea63f5f48866cdc7b88df800a4ace27ab8aa79c
Prior prediction benchmark on the same export; different test.
- usesSquare-root PSD area reduced row prediction error for 155 stored ferret spine simulations sci:sha256:c6b62c56e7eed382f976caaab16759babf3d92a5a67b336d34daedc7c98889af
Motivated the square-root area sensitivity rule and source simulation distinction.
- The largest contact holds a mean 47% of cleft size in 1,519 selected Allen V1 connections sci:sha256:002ee9e80347aa25617ae61940dca8f996330f58445ab6c2d2cb51b24097dbd9
Related contact concentration and dropout analysis in Allen V1 without matched activity; no data reused.
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesJoint error bounds permit zero orientation projection in 155 pooled ferret V1 spine records
Motivates extension of its fixed orientation projection to angle and weight uncertainty. No code reused.
- usesPSD weights raised uniform-loss reversal risk in 155 pooled ferret spine records under a fixed projection model
Extends its fixed projection and targeted-loss study with deterministic uniform-loss probability brackets; no code or data tables reused.