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The change in adjusted hippocampal theta deviation at six letters from encoding to maintenance had a 95% interval that included zero in 14 epilepsy patients

We tested the hippocampal theta deviation at six letters from the midpoint of the four- and eight-letter responses. We compared this deviation between encoding and late maintenance. Public SEEG from OpenNeuro ds004752 version 1.0.1 supplied 14 epilepsy patients, 62 sessions, and 2,561 selected trials. Each patient model included session, trial position, and preceding load terms. The mean maintenance-minus-encoding deviation was +0.0075 dB. Its 95% patient bootstrap interval was -0.229 to +0.245 dB. The exact two-sided sign-flip probability was 0.9529. The interval includes zero. It does not establish equal effects or a capacity limit. Patients had equal weight. Inference assumes independent patients and symmetric null effects for the sign-flip test. The package preserves source features, metadata, object versions, code, all patient fits, resampling draws, raw check records, figures, and reproduction instructions. This is a new contrast in a reused cohort. Three complete raw files passed fresh full-file hash checks, one at each native sample rate.

hippocampus · theta power · verbal working memory · intracranial EEG · SEEG · middle-load deviation · patient bootstrap

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4
  1. usesThe hippocampal theta load difference between maintenance and encoding had a 95% interval that included zero for 8 versus 4 letters in 14 SEEG patients sci:sha256:908e6a50a06004ae7aee55957ef3e0000789f1ff918baf6278e8de910b59ab7d

    This study uses the preserved native-window band features, source metadata, fixed raw object versions, and extraction code. It tests the 6-letter deviation from the endpoint midpoint and its change between task periods. It uses the same patients and signals; it is not an independent replication.

  2. usesdoi:10.18112/openneuro.ds004752.v1.0.1

    The analyzed SEEG source is OpenNeuro ds004752 version 1.0.1; the publication identifies this snapshot and the preserved raw object hashes.

  3. doi:10.1038/s41597-020-0364-3
  4. doi:10.7554/eLife.78677

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