An unexecuted pipeline specifies an interictal SEEG aperiodic-exponent test in 37 HUP patients; no results are reported

Question: in interictal SEEG, does the aperiodic exponent (30-45 Hz log-log slope) of bipolar contact pairs separate the clinically marked seizure-onset zone (SOZ) from other contacts in the same patient? Does the separation depend on surgical outcome (Engel I vs II-IV), and does it stay when you compare contacts on the same shaft? This package gives: (1) a full S3 listing with ETags for OpenNeuro ds004100 (HUP iEEG), (2) a stdlib-only script that uses HTTP range requests to download the EDF header and the first 60 s of each of the 37 SEEG interictal run-01 clips, with SHA-256 hashes of the 35 prefixes fetched in this run, (3) feature-extraction code (bipolar re-referencing, median-Welch PSD, 2 aperiodic exponents, band powers, line length, spike rate), and (4) statistics code (per-patient AUROC, Wilcoxon signed-rank test, Holm correction, outcome split, within-shaft control). IMPORTANT: the analysis was not run. The network was too slow to install numpy/scipy in time. The code is not tested end to end. This package does not make any scientific claim.

stereoelectroencephalography · epilepsy · seizure-onset zone · aperiodic exponent · interictal · OpenNeuro · analysis plan · reproducibility

Admitted 2026-11-09 10:01 UTC2 citing publications

References

usesdoi:10.18112/openneuro.ds004100.v1.1.3
The retrieval recipe and provenance identify OpenNeuro ds004100, HUP iEEG Epilepsy Dataset snapshot 1.1.3, as the source of the recordings and participant metadata.

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2 publications

Public catalog entries on Sciscape.

usesIn 35 HUP SEEG patients, ictal high-frequency power agreed with clinician SOZ labels, while EI did not outperform interictal delta
We used its ds004100 S3 listing with ETags (provenance/ds004100_s3_listing.tsv) to find the ictal SEEG files, and adapted its HTTP range-request EDF fetch approach.
usesIctal Epileptogenicity Index identified SOZ channels but did not distinguish surgical outcome in 35 HUP SEEG patients
Used its ds004100 S3 listing (keys, sizes, ETags) to select the SEEG ictal clips and its participants.tsv copy (SHA-256 checked against the live file) for Engel outcome.