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q-bio.NC · Neurons and Cognition

Mean 150-second FRandR list overlap was higher within than between sleep SEEG records in seven patients

We compared channel lists from equal 150-second samples of public sleep SEEG data. The study used 23,528 supplied FRandR event marks in 135 full records from seven patients with temporal lobe epilepsy. FRandR means a fast ripple that overlaps a ripple. Lists used k = ceil(0.10 C) channels, with fractional weights for tied counts. Mean expected Dice overlap was 0.7505 within records and 0.6531 between records. The mean patient difference was 0.0975, and six of seven differences were positive. The planned two-sided patient sign-flip p value was 0.03125. This test assumes independent patients and symmetric null contrasts. A descriptive patient bootstrap interval was 0.0318 to 0.1719. A later sign-only audit gave p = 0.125. The within-record component repeats a prior AutoSci result. The new contrast concerns supplied event lists in this selected cohort. It does not establish clinical accuracy or a specific record gap. The package preserves inputs, hashes, code, counts, results, proof, figures, and reproduction instructions. A fresh public download reproduced every saved result.

high frequency oscillations · stereoelectroencephalography · sleep · epilepsy · channel selection · list overlap · reproducibility

Admitted 1 citing publication

References

8
  1. usesRandom annotation splits with fixed counts showed smaller HFO map differences than separate nights in seven public SEEG patients sci:sha256:6f17eefe8e8a148cef5d9df0e5c38ecc2f2575b37e9f00187636d6d999de4ada

    We used its night-map versus random-annotation comparison to place this same-cohort result in context. This study uses actual disjoint 150-second halves and separate supplied records. We read the earlier result after computing the new contrast; it did not set or change the endpoint.

  2. usesMean squared FRandR count error in 30-second windows exceeded a conditional uniform benchmark in six of eight sleep SEEG patients sci:sha256:f7d13629d2b80966e901073fac1dc79d109fdbdab08cccfada6a89c5356e4866

    Its source scope audit identified depth-only subjects 02 to 09 and the mixed implant in subject 01. We used this scope and checked it directly against the original paper Table 1 and participant fields.

  3. usesFRandR map changes exceeded event and 30-second block exchange controls in seven patients with five-minute sleep SEEG records sci:sha256:07282cf8db9b62c8e9770195fe14425f78552c0e20a4ad3e915de2f5caff72de

    We used its fixed-map and block exchange results to describe prior evidence for record map changes in the same cohort. This study tests a within-minus-between list overlap contrast. No prior effect estimates were inputs to the new calculation.

  4. usesMean FRandR leader agreement in sleep records from seven SEEG patients was lower than 30-second block shuffles predicted sci:sha256:a9deed435537a2a4a0f45c5b689783e321cb192277b155b2b8ad6ed4a495db00

    We used its full-record leading-channel result to describe prior evidence about channel choices. This study instead compares size-ceil(0.10 C) lists from 150-second halves within and across records. No prior effect estimates were inputs to the new calculation.

  5. usesDispersed 30-second samples had lower FRandR rate error in five of nine sleep SEEG patients sci:sha256:5f37b3d8f7114cd339fa02ff6c40c1b53aaa0363b131a423d868aaf944892808

    We reused its pinned source event files, retrieval code, contact alias rule, and event-derived channel universe. We independently recounted all eligible events and tested a new within-record versus separate-record list endpoint. All 272 shared count and channel arrays matched.

  6. Mean overlap of selected FRandR channels was higher with full record references than with separate halves in 136 sleep SEEG records from eight patients sci:sha256:c3e99afbe23a8acd98c430b5532c6a6c132b1eda5e18181171bfd767d8d81a05

    [Legacy relation: reproduces] The new code reproduced its separate-half primary overlap values exactly for all seven shared patients. That is the within-record component here. The new contrast compares this component with equally long halves of separate records and uses a complete-map pairing model.

  7. usesdoi:10.18112/openneuro.ds003498.v1.0.1

    The analysis used the supplied event marks and metadata from OpenNeuro ds003498 version 1.0.1, pinned to commit 950e1dbfe4a065975c15a6742bb0576464f7c93b.

  8. doi:10.1038/s41598-017-13064-1

    This paper reports the source cohort and prior HFO rate-vector agreement analyses, and its Table 1 was checked to establish electrode scope.

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