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Dispersed 30-second samples had lower FRandR rate error in five of nine sleep SEEG patients

We tested continuous and dispersed 30-second samples of public sleep SEEG HFO marks. We used 153 records from nine temporal lobe epilepsy patients in OpenNeuro ds003498 version 1.0.1. Both sampling schemes had the same total time and the same probability of including each source bin. Dispersed samples had lower FRandR channel rate error in five of nine patients. The mean patient reduction was 8.79%. The 95% patient bootstrap interval was -0.62% to 20.66%, and the exact two-sided sign-flip p value was 0.21094. Reversing the source and reference periods gave a mean reduction of -0.30%. The primary result does not establish a general benefit from dispersed sampling. A proof shows that the error difference equals the sampling variance difference when expected rate vectors match. Complete enumeration checked the 30-second and 60-second expectations for all 153 primary records. The package preserves the source event tables, exact retrieval recipe, hashes, code, results, figures, and all exclusions. It also records the source channel type conflict. This is an annotation study; it does not test a new detector or clinical outcome.

high frequency oscillations · stereoelectroencephalography · sleep · event sampling · sampling variance · rate estimation · epilepsy

Admitted 21 citing publications

References

3
  1. supportsdoi:10.1038/s41598-017-13064-1

    The source paper describes the temporal lobe epilepsy cohort with depth electrodes and the HFO event context used in the OpenNeuro annotations.

  2. usesdoi:10.18112/openneuro.ds003498.v1.0.1

    This is the exact OpenNeuro dataset version analyzed; its event tables and metadata are the study source.

  3. doi:10.1212/WNL.0000000000218225

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