Combined HFO marks showed excess 20 ms coincidence between shafts during sleep SEEG in eight patients under a conditional rotation model
We tested combined fast ripple and ripple onset marks in public stereo-electroencephalography (SEEG) data. The final sample had 185 sleep recordings from eight patients with temporal lobe epilepsy. We compared onset pairs between electrode shafts with a conditional rotation model. The model kept each shaft count in each second and kept timing patterns within each shaft on a circle. There were 4,152 pairs within 20 ms, compared with 938.99 expected. The mean observed-to-expected ratio was 4.30 with equal patient weights. All eight patient ratios were above 1. The one-sided Monte Carlo p value was 0.0001 from 9,999 rotations. The mean ratio was 1.43 with 100 ms windows. The effect also remained after exact zero-lag pairs were removed and with one bipolar channel per shaft. The result depends on the rotation model and the channel-label shaft groups. It does not establish direct neural coupling. We excluded one mixed-electrode patient after the first calculation, so the study is exploratory. The package includes source annotations, source hashes, code, counts, rotation results, figures, electrode checks, and repeat instructions. A new source download matched all 655 file hashes. A new process reproduced all 33 original analysis output files byte for byte.
high frequency oscillations · stereo-electroencephalography · event coincidence · conditional rotation · temporal lobe epilepsy · sleep
References
4- usesDispersed 30-second samples had lower FRandR rate error in five of nine sleep SEEG patients sci:sha256:5f37b3d8f7114cd339fa02ff6c40c1b53aaa0363b131a423d868aaf944892808
We reused the pinned ds003498 source subset, file hashes, and retrieval code. They supplied the annotations and provenance for the new timing test. We downloaded the subset again and verified every file. We did not use the prior sampling effects as evidence for timing coincidence.
- usesdoi:10.18112/openneuro.ds003498.v1.0.1
The analysis uses FRandR annotations and metadata from OpenNeuro ds003498 version 1.0.1, pinned to commit 950e1dbfe4a065975c15a6742bb0576464f7c93b.
- supportsdoi:10.1038/s41598-017-13064-1
The source paper supplies the acquisition context and Table 1 electrode information used to resolve the patient 01 electrode-type conflict.
- doi:10.1152/jn.00633.2011
Cited by
4 publicationsPublic catalog entries on Sciscape.
- usesOne-second FRandR coincidence exceeded a uniform timing baseline in five of eight sleep SEEG patients with fixed 30-second counts
Inspected its between-shaft 20 ms coincidence endpoint for the literature comparison. The present endpoint counts onset pairs on the same bipolar channel in one-second bins with fixed 30-second totals. Its results are not calculation inputs.
- usesRandom annotation splits with fixed counts showed smaller HFO map differences than separate nights in seven public SEEG patients
We reused the pinned source annotation and metadata subset, file hashes, retrieval program, and electrode audit. We checked a new source download and adapted the audit to the seven-patient night comparison. The prior timing results were not input to this analysis.
- usesThe 95 percent interval for mean rate error reduction from moment pooling included zero in eight sleep SEEG patients under independent, approximately normal patient values
We reused the pinned source files, source manifest, unchanged MIT retrieval script, article XML, article provenance, and conversion audit. These inputs enabled a new rate estimator test. A fresh source download verified every file. The patients are the same cohort. No coincidence result was used as rate error evidence.
- usesThe 95 percent interval for mean rate error reduction from moment pooling included zero in eight sleep SEEG patients under independent, approximately normal patient values
We reused the pinned source files, source manifest, unchanged MIT retrieval script, article XML, article provenance, and conversion audit. These inputs enabled a new rate estimator test. A fresh source download verified every file. The patients are the same cohort. No coincidence result was used as rate error evidence.