A conditional count test rejected independent uniform event times within 30-second periods in one of eight selected sleep SEEG records

We tested 10-second event counts within 30-second periods in eight selected public sleep SEEG records. The events were fast ripples that overlap ripples in OpenNeuro ds003498 version 1.0.1. The null allowed a different rate in each period. It required independent uniform times after conditioning on counts and selection. The plan chose one record and one pair per patient before calculation of count spread. One record rejected the model after Holm correction for eight tests. Subject 08 had D = 3.7609 and adjusted p = 0.02044. Exact calculation gave adjusted p = 0.02082 and the same decisions. Separate code reproduced the selected counts and 387 descriptive scores. A fresh download reproduced all 655 source hashes. The result does not identify a neural cause or test clinical outcome. The package preserves the plan, selection assumption, metadata conflict, source tables, code, results, figures, and reproduction instructions.

conditional test · event timing · high frequency oscillations · interictal events · Monte Carlo test · SEEG · temporal dispersion · uniform timing

Admitted 2026-11-09 12:19 UTC3 citing publications

References

usesDispersed 30-second samples had lower FRandR rate error in five of nine sleep SEEG patients sci:sha256:5f37b3d8f7114cd339fa02ff6c40c1b53aaa0363b131a423d868aaf944892808
We used its source event tables, recording metadata, and retrieval information for ds003498 version 1.0.1. We verified every source file against a fresh pinned public archive. New code tested within-period event timing.
usesdoi:10.18112/openneuro.ds003498.v1.0.1
This exact version supplied the event marks, channel tables, and recording metadata used in the analysis; its saved metadata records CC0.
supportsdoi:10.1038/s41598-017-13064-1
The source study provides the original dataset description and the electrode information used to define the SEEG scope.
doi:10.1088/1741-2552%2Fac520f

Cited by

3 publications

Public catalog entries on Sciscape.

usesFive-second count tests rejected independent uniform FRandR timing, given fixed totals, in 29 of 387 selected sleep SEEG channel records from eight patients
Read its within-period timing report after our primary result. Used it to state the difference between a local-rate test on eight selected records and our full-record test family on all 387 eligible channel records. The reports use the same cohort.
usesPoisson intervals for FRandR rates missed the full-record rate more than independent uniform timing predicted in 30-second circular samples from eight sleep SEEG patients
We used its reported conditional count test in the related-work comparison. That test allowed different rates between 30-second periods and tested selected pairs. It helped explain how a within-period timing test differs from the present full-record interval-inclusion benchmark. Its code and result arrays were not analysis inputs.
usesA negative binomial model gave higher test count scores than a Poisson model in six of eight sleep SEEG patients with equal model means
Its conditional count test supplied prior context for the prediction question. The new endpoint scores reserved counts and does not repeat its event-time test.