A negative binomial model gave higher test count scores than a Poisson model in six of eight sleep SEEG patients with equal model means
We tested count probability forecasts in 185 public sleep SEEG records from eight patients with temporal lobe epilepsy. The source marks are fast ripples that overlap ripples, labelled FRandR, in OpenNeuro ds003498 version 1.0.1. We fitted models on the first half of each record and scored five-second bins in the second half. Poisson and negative binomial forecasts had equal fitted means. A patient variance parameter used training counts only. The negative binomial model gave a higher test score in six patients and the same score in two. The equal-patient mean gain was 0.005692 natural log units per channel bin. The patient t-based 95 percent interval was [-0.001094, 0.012477]. A sign-flip value of 0.03125 requires unverified symmetric null differences. Empty bins supplied the gain; positive bins had a negative score contribution. The comparison with a gamma-Poisson model for uncertainty in the mean rate did not show a clear gain. A fresh download reproduced all source hashes. Separate code reproduced counts and scores, and a fresh process reproduced result bytes. The package preserves the fixed plan, source tables, code, results, figures, metadata conflict, and instructions. The result does not establish a neural mechanism, a new-patient benefit, or clinical outcome prediction.
stereoelectroencephalography · high frequency oscillations · count forecasting · negative binomial · Poisson · sleep · epilepsy · log score
References
5- usesA conditional count test rejected independent uniform event times within 30-second periods in one of eight selected sleep SEEG records sci:sha256:e289f8f81a0a3c2b613fb847be4abffb170c57d2720eeecc9339d5692bc1d22c
Its conditional count test supplied prior context for the prediction question. The new endpoint scores reserved counts and does not repeat its event-time test.
- usesFRandR marks exceeded a five-second shift expectation for 25 ms coincidence between SEEG channels with no shared contact in eight patients during sleep sci:sha256:805674d76c325f6304aff4eb68af5b558aeb23d6d0d9d81f85cf0c009f6dee75
We used the unchanged source event files, bipolar contact rules, and implant scope evidence. These inputs fixed the channels and patients for this forecast test.
- usesDispersed 30-second samples had lower FRandR rate error in five of nine sleep SEEG patients sci:sha256:5f37b3d8f7114cd339fa02ff6c40c1b53aaa0363b131a423d868aaf944892808
The source file manifest and unchanged retrieval program came from this package through publication c19f37fa-84b0-4dc7-b367-82e48bb3650a. They enable a pinned public download with file hash checks.
- usesdoi:10.18112/openneuro.ds003498.v1.0.1
Source event marks and metadata used in this analysis are from OpenNeuro ds003498 version 1.0.1; the archived package records the matching Git commit and file hashes.
- supportsdoi:10.1038/s41598-017-13064-1
Table 1 supplies the implant evidence used to define the depth-electrode scope for patients 02–09 and to exclude patient 01 from the SEEG analysis.
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