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The STE spike selection AUC change interval included zero within shafts in the first hour of 17 SEEG records under independent, exchangeable patient sampling

We tested whether released spike scores improve local seizure onset channel ranking above counts selected by artifact scores. We used public sleep SEEG from OpenNeuro ds005398 version 1.1.3. The fixed primary test used STE events in the first hour and a spike threshold of 0.5. It included 474 SOZ versus other channel pairs on 38 shafts in 17 patients. Mean patient AUC was 0.645847 for HFO counts and 0.647391 for spike HFO counts. The paired mean change was 0.001544. Its nominal 95 percent patient bootstrap interval was -0.035453 to 0.039583 under independent, exchangeable patient sampling. The interval included zero. The test did not establish a gain or equivalence. All 20 fixed comparisons are reported. MNI results show that score selection can affect detector counts and ranks differently. The package preserves public input bytes, versions, hashes, new code, count and pair tables, patient results, a figure and repeat instructions. Fresh public checks matched 94 input objects or EDF headers. A separate parser checked 38,550 counts. Repeated analysis matched seven numerical files exactly. This reused cohort does not establish external classifier performance or clinical benefit.

high-frequency oscillations · stereoelectroencephalography · seizure onset zone · channel ranking · within-shaft comparison · patient bootstrap

Admitted 1 citing publication

References

4
  1. usesMean STE AUC within supplied brain regions was 0.684 in the first hour of 16 public SEEG sleep records sci:sha256:bacdf8c0cdf3d7cc0acf20766dc9e3574038f0fa981aa2bb904f861527ed92a2

    This publication supplied the exact compressed public source tables, EDF headers, pinned retrieval manifest and retrieval code. We inspected the code, checked all local hashes and repeated public byte retrieval. New count and effect code tested artifact and spike score selection.

  2. The 95 percent patient interval for mean STE AUC within shafts was above 0.5 in the first hour of 17 SEEG sleep records under independent, exchangeable patient sampling sci:sha256:af5b5ab927df01a4465dd7f63bb7cd921194d0dda5609be020b79257bd26194a

    [Legacy relation: reproduces] New code reproduced the reported first-hour within-shaft raw STE mean AUC 0.639257 and raw MNI mean AUC 0.472516 on the same 17 patients, 38 shafts and 474 pairs. This is a computational reproduction on reused data. We then tested the added rank effect of source artifact and spike score selection.

  3. usesdoi:10.18112/openneuro.ds005398.v1.1.3

    The analysis used the released sleep event tables, channel and participant tables, and EDF headers from OpenNeuro ds005398 version 1.1.3. The source manifest preserves public paths, object versions, and byte hashes.

  4. doi:10.1111/epi.18545

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