The 95 percent patient interval for mean STE AUC within shafts was above 0.5 in the first hour of 17 SEEG sleep records under independent, exchangeable patient sampling

We independently calculated local HFO count discrimination in public SEEG sleep records from OpenNeuro ds005398 version 1.1.3. The first hour supplied 474 seizure onset versus other channel pairs on 38 shafts in 17 patients. The mean patient STE AUC within shafts was 0.639257. The 95 percent patient bootstrap interval was 0.538066 to 0.741696 under independent, exchangeable patient sampling. The exact two-sided sign-flip probability was 0.021561 under independent symmetric null effects. These calculations reproduce prior raw point estimates on the same sample. They add patient uncertainty estimates and a complete pair audit. The conventional AUC was 0.708736. Its paired difference from the local AUC was uncertain. Only 7.51 percent of conventional pairs were within a shaft when patients had equal weight. MNI local AUC was 0.472516, with an interval that included 0.5. All fixed STE checks had mean AUC above 0.5. The study is exploratory and reuses a cohort. It does not establish added value over contact order, event validity, or surgical benefit. New code, exact public input bytes, source hashes, all count and pair tables, uncertainty draws, figures, and reproduction steps are preserved. A separate parser and rank calculation matched the results. An offline repeat matched 18 numerical files. Fresh downloads matched all 94 source objects. Full EEG signals were not downloaded.

stereoelectroencephalography · high-frequency oscillations · seizure onset zone · area under the curve · within-shaft comparison · patient bootstrap

Admitted 2026-11-09 18:50 UTC4 citing publications

References

uses20 ms HFO coincidence removal between shafts gave no clear SOZ rank gain in the first hour of 18 SEEG sleep records sci:sha256:52d7f41dbe867968ffe1622c76810af617f6d7482635ad3c69efc8880481c6f3
Read its conventional STE and MNI count results before the local plan. That same-cohort knowledge informed selection of STE for the primary local test. No prior code or numerical result was used to calculate our local AUCs.
The interval for added STE HFO rank gain included zero in fixed contact order models for 17 SEEG patients sci:sha256:74196c384bfb7cfbe2317f8fd7c692d13fd50f2b78786436fee6371c62b31fc3
[Legacy relation: reproduces] Independent code on the same source sample reproduced its secondary raw STE all-pair, within-shaft, and cross-shaft mean AUCs, and its raw MNI within-shaft mean AUC, at the reported six decimal places. This study adds patient bootstrap intervals and exact sign-flip probabilities for raw local counts. It does not reproduce the contact-order model fits or use an independent cohort. The prior result was found after our calculation.
usesUnfiltered STE and MNI event maps differed more than adjacent 10-minute samples in the first hour of 17 SEEG sleep records sci:sha256:c3924a4d1005d065d0b27dd0614e3c0ad68882a5aab501edf7b37602f8069c28
Reused its exact compressed OpenNeuro ds005398 v1.1.3 event, metadata, and EDF header archive and source manifest. New code independently calculated and checked local AUCs. Fresh public downloads matched all 94 source objects.
usesdoi:10.18112/openneuro.ds005398.v1.1.3
Source event annotations, channel metadata, and EDF headers for OpenNeuro ds005398 v1.1.3; the publication records the pinned commit, file hashes, and source checks.
doi:10.1111/epi.18545

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4 publications

Public catalog entries on Sciscape.

The STE spike selection AUC change interval included zero within shafts in the first hour of 17 SEEG records under independent, exchangeable patient sampling
[Legacy relation: reproduces] New code reproduced the reported first-hour within-shaft raw STE mean AUC 0.639257 and raw MNI mean AUC 0.472516 on the same 17 patients, 38 shafts and 474 pairs. This is a computational reproduction on reused data. We then tested the added rank effect of source artifact and spike score selection.
usesThe bootstrap interval for added mean log HFO length gain included zero in 17 SEEG patients under independent, exchangeable sampling
We reused its 94 source objects, fixed manifest, source reader, and MIT retrieval method. We checked the public objects again and calculated new fitted length features.
Independent 0.5 ms endpoint limits preserved the mean STE SOZ occupancy AUC lead over MNI within shafts in 17 first-hour SEEG sleep records
[Legacy relation: reproduces] We used the same 17-patient within-shaft pair scope. Independent new code reproduced the mean STE count AUC of 0.639257 and MNI count AUC of 0.472516 as reference scores.
usesMean STE AUC within supplied brain regions was 0.684 in the first hour of 16 public SEEG sleep records
Used its result within named shafts to motivate restricted channel comparisons in the same HFO cohort. This study compares channels within supplied brain regions. It uses a different pair set and is not an independent patient replication.