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20 ms HFO coincidence removal between shafts gave no clear SOZ rank gain in the first hour of 18 SEEG sleep records

We tested a fixed 20 ms rule in the first hour of 18 public SEEG sleep records. We removed each STE event with an onset on another named electrode shaft within 20 ms. Mean patient AUC was 0.7188 before removal and 0.7178 after removal. The mean change was -0.0010; its 95% patient bootstrap interval was [-0.0426, +0.0278]. Removal discarded 34.2% of the STE event marks. These data did not show a clear SOZ rank gain. Eleven patients gained AUC, five lost AUC, and two had equal AUC. In the largest-loss case, removal discarded all 14 STE events from the two SOZ channels. Fixed time-limit, detector, and time-window checks also gave uncertain mean changes. The test uses released event marks and clinical labels. It does not estimate surgical benefit. The package contains source archives, hashes, event witness links, code, figures, and full patient results. Separate source parsing and timing checks passed. All 16 numerical files matched an offline repeat.

high-frequency oscillations · stereoelectroencephalography · seizure onset zone · event timing · electrode shafts · area under the curve · epilepsy

Admitted 4 citing publications

References

4
  1. uses20 ms detector matches gave an uncertain SOZ rank gain over combined counts in the first hour of 18 SEEG sleep records sci:sha256:e2fb21fc2b8904e6e332f4adef0382d28035541049ea83d70d8da9f15b9adbb1

    This publication supplied the pinned ds005398 source archives, manifest, source parser, and AUC functions. We used them to test a new rule that removes same-detector events with a nearby onset on another shaft.

  2. usesdoi:10.18112/openneuro.ds005398.v1.1.3

    The study analyzed the first-hour released STE and MNI event marks, channel labels, participant metadata, and EDF headers from OpenNeuro ds005398 v1.1.3.

  3. doi:10.1684/epd.2015.0774
  4. supportsdoi:10.1111/epi.18545

    This is the source study cited for HFO morphology and epilepsy outcomes in the larger cohort.

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