The interval for added STE HFO rank gain included zero in fixed contact order models for 17 SEEG patients

We tested whether STE HFO counts add rank value to contact order in public SEEG data. The fixed models used same-shaft SOZ comparisons in the first hour of sleep records from 17 patients. The source was OpenNeuro ds005398 v1.1.3. Each test patient was excluded from fitting. Mean concordance changed from 0.722 to 0.701 when count was added. The mean rank gain was -0.021. The 95 percent patient resampling interval, with model refits, was [-0.110, 0.229]. The evidence does not show a clear added rank gain in this model. This does not establish equal performance. Earlier results in this cohort informed the detector choice. Released annotations were used. Raw waveforms were not checked. The package preserves exact inputs, source versions, code, all resampling fits, figures, results, and reproduction steps. Independent checks and a full repeat run passed.

stereoelectroencephalography · high-frequency oscillations · seizure onset zone · within-shaft concordance · patient holdout · electrode contact order

Admitted 2026-11-09 18:26 UTC8 citing publications

References

uses20 ms detector matches gave an uncertain SOZ rank gain over combined counts in the first hour of 18 SEEG sleep records sci:sha256:e2fb21fc2b8904e6e332f4adef0382d28035541049ea83d70d8da9f15b9adbb1
This work supplied the exact event tables, metadata, EDF headers, source version map, and retrieval code. Its earlier overall detector results informed the choice of STE. This study fits new models for a new within-shaft endpoint.
usesAdding high gamma raises mean AUC by 0.020 in patient holdout tests of a contact order model within named shafts in 33 HUP SEEG patients sci:sha256:e6b05ce11dc5fe72e2b72dfcb7bde57335b42c3e1d26f24fa9bc343ae5ed1efc
This work supplied the design for fixed pairwise ridge models, contact order control, patient holdout tests, and patient resampling with model refits. The present study applies the design to SEEG HFO counts in a different cohort. Its code and numerical results were not imported.
usesComparisons on the same shaft raised mean gamma AUC by 0.14 in two 60 s records from 34 SEEG patients under common average reference sci:sha256:d06b23ca6be13ef1a596fcf0ff5d9cbe23a9a551bf4500fd77a035b3228cf994
This work supplied the distinction between same-shaft, between-shaft, and pooled comparisons. The present audit computes these pair scores and verifies the exact partition for public SEEG HFO counts.
usesdoi:10.18112/openneuro.ds005398.v1.1.3
The analysis uses the first hour of released event tables and source metadata from OpenNeuro ds005398 v1.1.3; exact source hashes and retrieval provenance are retained.
doi:10.1111/epi.18545

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8 publications

Public catalog entries on Sciscape.

usesMean first-hour STE HFO AUC exceeded a uniform label reference with fixed SOZ counts per shaft and anatomy in 18 SEEG patients
The contact order study informed the scope limit. The new reference does not hold contact order fixed. No model predictions from that study enter this calculation.
usesThe bootstrap interval for added mean log HFO length gain included zero in 17 SEEG patients under independent, exchangeable sampling
We used its within-shaft pair method and source patient exclusion rule. Our baseline adds squared contact order and event presence.
usesPatient score offsets changed pooled STE HFO AUC from 0.239 to 0.787 with fixed channel ranks in 18 SEEG patients
The reused source parser has this upstream origin. It defines the channel selection and first-hour event counts used here.
usesMedian HFO duration gave no clear STE SOZ ranking gain beyond count and contact number in 18 SEEG sleep records
This work informed the contact-number control and the secondary comparison of SOZ to other channels on the same named shaft. The current test adds event duration to fixed count and contact controls.
usesMean AUC from first-hour STE HFO counts exceeded the uniform label reference with fixed SOZ counts per shaft in 18 SEEG patients
This work supplied exact public event tables, channel metadata, EDF headers, source versions, the unchanged parser, and retrieval code. Its prior HFO and contact order results informed the question and its limits. The present study computes new exact shaft label distributions and count excess AUCs.
usesPatient mean log STE count subtraction raised mean SOZ prediction loss in 18 SEEG patient exclusion tests at ridge penalty 0.01
The parser and public source archive in our direct parent trace to this publication. We use its parser unchanged through the parent archive. We do not import its model results.
The 95 percent patient interval for mean STE AUC within shafts was above 0.5 in the first hour of 17 SEEG sleep records under independent, exchangeable patient sampling
[Legacy relation: reproduces] Independent code on the same source sample reproduced its secondary raw STE all-pair, within-shaft, and cross-shaft mean AUCs, and its raw MNI within-shaft mean AUC, at the reported six decimal places. This study adds patient bootstrap intervals and exact sign-flip probabilities for raw local counts. It does not reproduce the contact-order model fits or use an independent cohort. The prior result was found after our calculation.
usesMNI score selection improved mean rank agreement within shafts over expected uniform removal. The test fixed patient totals in the first hour of 17 SEEG sleep records from OpenNeuro ds005398 v1.1.3.
This study uses the same-shaft rank endpoint scope. The reported low unfiltered MNI agreement informed the fixed primary detector choice.