Mean first-hour STE HFO AUC exceeded a uniform label reference with fixed SOZ counts per shaft and anatomy in 18 SEEG patients
This study tested high frequency oscillation (HFO) count ranks in 18 public SEEG patients. It used the first 3,600 seconds of sleep records from OpenNeuro ds005398 version 1.1.3. The reference fixed clinical seizure onset zone (SOZ) counts within each named shaft and source anatomical label. It gave all label subsets of that size equal probability. Mean STE count AUC was 0.718833. The exact reference mean was 0.681684. Mean excess was 0.037148, with a 95 percent patient bootstrap interval of [0.006877, 0.077788]. Only 32 of 493 blocks had both SOZ classes. A fixed disjoint contact check gave mean excess 0.010444, with interval [-0.007666, 0.029897]. Population intervals require independent, exchangeable patients. Reference probabilities require uniform conditional labels. This new analysis reuses a known cohort. It does not establish added value beyond contact order or clinical benefit. The package preserves source bytes, public versions and hashes, exact block distributions, code, results, figures, and run instructions. Independent checks and complete repeats from saved and fresh public inputs passed.
high frequency oscillations · stereoelectroencephalography · seizure onset zone · area under the curve · conditional reference · anatomy · patient bootstrap · epilepsy
References
6- usesMean AUC from first-hour STE HFO counts exceeded the uniform label reference with fixed SOZ counts per shaft in 18 SEEG patients sci:sha256:6243eb3f3ae31e57e51bb4f2c1ccc7b3cfea80f86ba1b310292ef936d9e8c0ca
The known shaft-only uniform label reference and its point estimates informed the new shaft plus anatomy reference. New code reproduced those point estimates on the same cohort. This is not independent patient validation.
- usesIn the first hour of 18 SEEG sleep records, 30-minute STE HFO maps had higher expected top 20% channel agreement than 5-minute maps sci:sha256:4d9fd5f1eaa1c005c1d288b2e596ac25540bdc558e18948e96c492be41759f09
The package supplied the pinned source manifest, 94 compressed source objects, selected parser functions, and public retrieval code. We retrieved every public object again. The new anatomy reference calculations use new code.
- usesThe interval for added STE HFO rank gain included zero in fixed contact order models for 17 SEEG patients sci:sha256:74196c384bfb7cfbe2317f8fd7c692d13fd50f2b78786436fee6371c62b31fc3
The contact order study informed the scope limit. The new reference does not hold contact order fixed. No model predictions from that study enter this calculation.
- usesdoi:10.18112/openneuro.ds005398.v1.1.3
The analysis used released detector marks and source metadata from OpenNeuro ds005398 version 1.1.3.
- doi:10.1212/WNL.0000000000004998
- doi:10.1111/epi.18545
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesSTE event counts gave higher mean SOZ AUC than event presence at 30 to 60 minutes in 18 SEEG sleep records
This publication supplied the pinned source archive, source manifest, selected parser functions, and public retrieval code. We retrieved all 94 public objects again. New code computed count versus presence scores and their exact pair decomposition.
- usesSTE event counts gave higher mean SOZ AUC than event presence at 30 to 60 minutes in 18 SEEG sleep records
This publication supplied the pinned source archive, source manifest, selected parser functions, and public retrieval code. We retrieved all 94 public objects again. New code computed count versus presence scores and their exact pair decomposition.