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Mean AUC from first-hour STE HFO counts exceeded the uniform label reference with fixed SOZ counts per shaft in 18 SEEG patients

This study tested HFO count ranks in 18 public SEEG patients. It used OpenNeuro ds005398 version 1.1.3 and the first 3,600 seconds of each sleep record. The exact reference kept the SOZ count on each named shaft fixed. It gave all label subsets of that size equal probability. Mean STE AUC was 0.719. The exact reference mean was 0.638. Mean excess was 0.081, with a paired patient bootstrap 95 percent interval of [0.019, 0.153]. A circular label check also gave a small group tail estimate. MNI mean excess was -0.014, with an interval that crossed zero. The package supplies an exact integer method for tied scores, full patient distributions, source annotations, public versions and hashes, code, results, figures, and reproduction steps. Independent checks and a repeat run passed. This is a secondary analysis of a known cohort. The probability result assumes the stated label reference. It does not establish added value beyond contact order or surgical benefit.

high-frequency oscillations · stereo-EEG · seizure onset zone · area under the curve · shaft label reference · exact distribution · intracranial EEG · OpenNeuro

Admitted 5 citing publications

References

4
  1. uses20 ms detector matches gave an uncertain SOZ rank gain over combined counts in the first hour of 18 SEEG sleep records sci:sha256:e2fb21fc2b8904e6e332f4adef0382d28035541049ea83d70d8da9f15b9adbb1

    The source archive and MIT retrieval code used here trace to this work through publication 6ead490c-8473-42f8-8387-7495e346a433. The original code notice and source metadata are preserved. Its earlier overall detector results were known before this secondary analysis.

  2. usesThe interval for added STE HFO rank gain included zero in fixed contact order models for 17 SEEG patients sci:sha256:74196c384bfb7cfbe2317f8fd7c692d13fd50f2b78786436fee6371c62b31fc3

    This work supplied exact public event tables, channel metadata, EDF headers, source versions, the unchanged parser, and retrieval code. Its prior HFO and contact order results informed the question and its limits. The present study computes new exact shaft label distributions and count excess AUCs.

  3. usesA low frequency score had 0.058 excess mean AUC under uniform shaft label permutations in 72 short SEEG records from 36 patients sci:sha256:739286ddbdfce424bcb3b92db5bc54ead8ee8a7bb7c626601848a9a283369a2c

    This work supplied the uniform shaft label reference, its exact expected AUC formula, and the circular label check for a different score and cohort. The present study adds a tested full exact distribution implementation and applies it to public HFO counts. No code or numerical data from that method study were imported.

  4. usesdoi:10.18112/openneuro.ds005398.v1.1.3

    This is the exact OpenNeuro dataset version analyzed. The retained source recipe and hashes identify the files used.

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