Temporal halves increased squared disagreement 2.76-fold for EEG theta-to-alpha scores in 95 ds008896 v1.0.1 records
We compared temporal halves with balanced random halves of the same posterior EEG score pools in 95 public OpenNeuro ds008896 v1.0.1 records: 32 people with CLN3 disease and 63 NIH volunteers. Each pool contained the first 28 retained four-second epochs, and each half contained 14 epochs. The score was the mean epoch log10 theta-to-alpha power ratio using a 19-channel mean reference. Temporal mean squared difference was 0.022883; the exact random-partition mean was 0.008292. The excess was 0.014592 squared log10 units (approximate 95% person bootstrap interval 0.007944 to 0.022452), and the ratio was 2.760 (interval 2.027 to 3.517). All six fixed cohort checks had positive excess intervals, and no one-person omission changed the excess sign. A fresh replay checked all 95 source records and 5,558 epochs. The result shows a split-choice effect in these processed records; it does not measure repeatability across visits, establish a neural cause, or support a causal or clinical interpretation. Retained epochs need not be continuous, and source processing and missing covariates limit interpretation.
EEG · theta-to-alpha ratio · temporal split · random partition · epoch order · CLN3 disease · finite-population variance · reproducibility
References
5- usesTemporal halves had greater mean squared disagreement in fixed alpha EEG lag matrices than balanced random halves for the first 200 accepted seconds of 88 processed ds004504 v1.0.9 records sci:sha256:3e81b513257f07b170b662f648e2cdc93fe7c631b157a12769d529d1e51751bb
Its temporal versus random half comparison for EEG lag matrices informed the question. This study tested a different scalar endpoint and a different public cohort.
- usesThe 95% interval included zero for the Fz versus 19-channel mean change in the CLN3 versus volunteer theta-to-alpha contrast using 80 seconds per person in 95 ds008896 records sci:sha256:c7168c6fd457a7c40b234b7dcdd5819e4d60536686faad4c4b6a97efb9e77a6d
Used all 95 checked spectral files, 292 source metadata files, locked retrieval receipts, and unchanged extraction and retrieval code. These inputs enabled the new temporal versus random score split test.
- usesIndependent ±3 dB epoch power gains reversed the Fz theta-to-alpha CLN3–HV contrast using 95 ds008896 records’ first 20 epochs sci:sha256:fd1be20a76258bc9af1ceb8c65647ef33286b456e6ceeb4c25f110e6ec59b01c
After the primary analysis, its common within-epoch power-gain model informed an added algebraic interpretation. The model leaves each epoch ratio, and thus our primary temporal and exact random quantities, fixed. It did not supply the primary split test.
- usesdoi:10.18112/openneuro.ds008896.v1.0.1
Analyzed source dataset, version 1.0.1; the recorded dataset metadata identifies its license as CC0.
- doi:10.3389/fnins.2017.00425
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