Bilateral targets shared fewer sites than degree-specific count controls in eight selected worm brain maps

We tested if target use of sites with different numbers of targets explains a prior bilateral shared-site deficit. Eight public C. elegans chemical synapse maps supplied a fixed 162-cell panel. New controls kept each source-target count, each site target count, and each target count within each exact site degree for its source. Observed bilateral shared-site totals were 0.732 to 0.886 times the control means. All eight totals remained below those means. Seven were below the pointwise central 95 percent control ranges in the main run. Thus target preference for site degree alone did not account for the direction of the prior result in this panel. Finite Markov chains, omitted local geometry and different animals limit inference. No activity or synaptic release was measured. The package has code, aggregate results, input hashes and a separate-data retrieval script.

C. elegans · polyadic synapses · bilateral neurons · conditional randomization · site degree · shared release