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q-bio.NC · Neurons and Cognition

Early bipolar gamma change maps had more repeat agreement than baseline change maps after power and position controls in two seizure files per patient for 28 SEEG patients

We tested whether early seizure gamma change maps repeat more than equal-length baseline change maps after power and contact position controls. We used OpenNeuro ds004100 version 1.1.3 and the first two selected seizure files per patient. The fixed analysis retained 28 patients and 3,042 matched bipolar contact pairs. One common design removed shaft intercepts, contact position terms, and both initial baseline power vectors from every map. Mean early residual correlation was 0.527. Mean baseline residual correlation was 0.133. The mean paired difference was 0.394, with a 95 percent patient bootstrap interval of 0.252 to 0.534. The exact two-sided sign-flip probability was 0.00002145. Population inference requires independent, exchangeable patients. The sign test also requires symmetric signs under its null. All nine planned alternatives are reported. Baseline choice changed the estimate. This reused clinical cohort does not establish clinical accuracy or treatment benefit. The package preserves the local fixed plan, all 64 source power files, source versions and range hashes, code, pair and patient results, bootstrap draws, figures, and reproduction commands. Fresh source retrieval independently rebuilt all 757,770 saved power values. A separate analysis process reproduced all nine numerical files exactly.

stereoelectroencephalography · epilepsy · gamma power · seizure · repeatability · intracranial EEG · baseline control · residual correlation

Admitted 2 citing publications

References

6
  1. usesBipolar gamma power had mean clinical onset mark AUCs of 0.900 at 0 to 10 seconds and 0.883 at 10 to 20 seconds within named shafts in 26 ds004100 SEEG patients sci:sha256:907aa78467fe5bfb0a76cd59da5caa7cbfb46102973ed12c999a62fce1d8acdf

    This publication supplied the unchanged 64 power arrays, source metadata, range recipes, extraction code, and two raw examples. We matched pairs across its selected files and checked its power values against fresh public signal retrieval.

  2. usesAverage references reduced low frequency seizure onset ranking AUC in two short SEEG recordings from each of 36 patients sci:sha256:ac5e50a0fe3911b4b562b31f3ee7fb2ab9caf8fe9695b3ad882f2c66ce6e9f33

    The preserved input extraction uses its versioned range transport and EDF layout methods. We used the inherited range transport for the fresh source check and a separate NumPy signal reader for power calculation.

  3. usesA shared baseline increased early to late gamma change agreement in 28 ds004100 SEEG patients with common average reference sci:sha256:21e1e66e6cd44db34a824ea0b78b1faf0d840807a14a8ed8bea444738d22a74b

    Its shared baseline result informed the new fixed comparison. We tested early agreement across separate seizure files against baseline change agreement, with both initial baseline power vectors removed from every map.

  4. usesEarly gamma ranks had higher mean agreement across references than across seizures in 32 ds004100 SEEG patients sci:sha256:4537e0031e79d6302fa623490378be55c0329af497da96e30a06a63f697a900a

    Its extraction code and file selection form the input data chain. The package preserves that code and selection. New checks independently rebuilt all saved powers from the fixed public signal ranges.

  5. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analyzed recordings are from OpenNeuro ds004100 version 1.1.3.

  6. doi:10.1016/j.clinph.2017.03.040

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