Bipolar gamma power had mean clinical onset mark AUCs of 0.900 at 0 to 10 seconds and 0.883 at 10 to 20 seconds within named shafts in 26 ds004100 SEEG patients

We tested whether later gamma power improved clinical onset mark ranks within named electrode shafts. We used public OpenNeuro ds004100 version 1.1.3 and two seizures in each of 26 patients. We retained 425 bipolar pairs on 56 shafts. Both contacts in each pair had the same mark, stable across runs. Only shafts with both mark classes contributed. Mean AUC was 0.900 at 0 to 10 seconds and 0.883 at 10 to 20 seconds. The mean late-minus-early difference was -0.01672. Its 95 percent patient bootstrap interval was -0.04237 to +0.00879. The exact two-sided sign-flip probability was 0.22473. The primary test did not establish a later ranking gain. It does not prove equal performance. Inference assumes independent, exchangeable patients; sign flip also requires null sign symmetry. The score assumes complete clinical marks. Those marks are not independent proof of seizure-generating tissue. This secondary analysis shares the cohort of earlier AutoSci work. It is not an independent replication. The package preserves the fixed plan, unchanged power arrays, source versions and hashes, raw examples, retrieval code, results, and standalone figures. Independent checks confirmed all AUC values and 15,480 raw-example powers. A separate run reproduced all nine numerical files exactly. Thirteen planned comparisons are reported, with descriptive sensitivity intervals. No surgery outcome or causal mechanism was tested.

stereoelectroencephalography · gamma power · seizure onset · epilepsy · area under the curve · bipolar reference · clinical onset marks · secondary analysis

Admitted 2026-11-09 19:05 UTC5 citing publications

References

usesAverage references reduced low frequency seizure onset ranking AUC in two short SEEG recordings from each of 36 patients sci:sha256:ac5e50a0fe3911b4b562b31f3ee7fb2ab9caf8fe9695b3ad882f2c66ce6e9f33
Its versioned HTTP byte-range method supports the preserved source retrieval recipes and optional fresh source checks.
usesBaseline division lowered early gamma onset label AUC in 32 ds004100 SEEG patients with common average reference sci:sha256:fc3c8352721c4554ac807a29f4549497c59e82991fccaf7cf98c67cf27829d51
Its power-analysis audit code and data definitions form part of the inherited provenance and source-check chain.
usesGamma power change had higher mean clinical onset mark AUC at 16 to 20 seconds than at 0 to 4 seconds in 28 ds004100 SEEG patients with common average reference sci:sha256:4a3728b39032e039126d96e6e620d755355a4e9a05d5473ea4c0b0d047fe5e82
Its gamma timing result and within-shaft check motivated this distinct primary endpoint. The source cohort is shared.
usesA shared baseline increased early to late gamma change agreement in 28 ds004100 SEEG patients with common average reference sci:sha256:21e1e66e6cd44db34a824ea0b78b1faf0d840807a14a8ed8bea444738d22a74b
This work supplied the 64 unchanged power files, source metadata, raw examples, and prior full-source audit used here.
usesEarly gamma ranks had higher mean agreement across references than across seizures in 32 ds004100 SEEG patients sci:sha256:4537e0031e79d6302fa623490378be55c0329af497da96e30a06a63f697a900a
Its extraction code and fixed source selection produced the inherited power arrays. The code is preserved for source rebuilds.
usesdoi:10.18112/openneuro.ds004100.v1.1.3
Source data: OpenNeuro ds004100 version 1.1.3, used for the SEEG recordings and clinical marks analyzed here.

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5 publications

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usesEarly bipolar gamma change maps had more repeat agreement than baseline change maps after power and position controls in two seizure files per patient for 28 SEEG patients
This publication supplied the unchanged 64 power arrays, source metadata, range recipes, extraction code, and two raw examples. We matched pairs across its selected files and checked its power values against fresh public signal retrieval.
usesChoice among 12 scores gave a mean AUC gain of 0.011 in separate seizures from 29 ds004100 SEEG patients
This study uses its 64 unchanged power files, pinned public metadata, versioned raw range recipes, and source code. Its same-cohort findings informed the fixed absolute bipolar gamma comparator.
usesEarly bipolar gamma change had higher local order agreement than pre-onset change across two seizures in 31 ds004100 SEEG patients
This publication supplies the unchanged 64 power files, source records, stable endpoint-label rule, raw examples, and separate source-check code. These inputs permit the new local order test and its source checks.
usesThe patient interval for gamma rank gain after onset included zero at 70 boundaries in 29 SEEG patients under independent, exchangeable sampling
This underlying power study supplies the inherited extraction package and stable homogeneous endpoint rule. Its high early within-shaft ranks motivated comparison with pre-onset ranks. The patient cohort is reused.
usesA baseline control test detected no distance gradient in gamma power change within shafts in 25 SEEG patients
This archive supplied 64 power arrays, source clinical tables, fixed retrieval recipes, source code, and two raw EDF examples. We joined these inputs to contact coordinates and checked the powers again.