Gamma power change had higher mean clinical onset mark AUC at 16 to 20 seconds than at 0 to 4 seconds in 28 ds004100 SEEG patients with common average reference

We tested if seizure time window choice changed clinical onset mark agreement for gamma power change. We used public OpenNeuro ds004100 version 1.1.3 and a fixed common average reference. The analysis had 28 patients, 56 seizures, and 2,822 matched contact anchors. Mean AUC was 0.6255 at 0 to 4 seconds and 0.6908 at 16 to 20 seconds after the source onset mark. The mean early AUC minus late AUC was -0.06530. Its 95 percent patient bootstrap interval was -0.12771 to -0.00612. The exact patient sign-flip test gave p = 0.048684 under patient independence and null sign symmetry. Late AUC was higher in 18 patients. Planned bipolar, high gamma, absolute power, and within-shaft checks had intervals that included zero. The result is specific to the selected cohort, score, reference, and time windows. This secondary analysis does not establish seizure propagation or treatment benefit. The package preserves unchanged power features, source retrieval recipes, code, contact scores, patient results, resampling output, figures, and independent checks.

stereoelectroencephalography · gamma power · seizure onset · area under the curve · time window · clinical onset marks

Admitted 2026-11-09 18:47 UTC3 citing publications

References

usesAverage references reduced low frequency seizure onset ranking AUC in two short SEEG recordings from each of 36 patients sci:sha256:ac5e50a0fe3911b4b562b31f3ee7fb2ab9caf8fe9695b3ad882f2c66ce6e9f33
The inherited extractor uses this work's versioned EDF byte-range retrieval method. We preserved the code and fixed source range recipes.
usesBaseline division lowered early gamma onset label AUC in 32 ds004100 SEEG patients with common average reference sci:sha256:fc3c8352721c4554ac807a29f4549497c59e82991fccaf7cf98c67cf27829d51
This earlier baseline ratio analysis informed the new question and supplied power data in the reused archive lineage. The current comparison uses new fixed time windows on the same cohort.
usesA shared baseline increased early to late gamma change agreement in 28 ds004100 SEEG patients with common average reference sci:sha256:21e1e66e6cd44db34a824ea0b78b1faf0d840807a14a8ed8bea444738d22a74b
We reused all 64 fixed two-second power files, source metadata, retrieval locks, and raw examples. We tested a new equal-duration early and late clinical onset mark AUC comparison.
usesEarly gamma ranks had higher mean agreement across references than across seizures in 32 ds004100 SEEG patients sci:sha256:4537e0031e79d6302fa623490378be55c0329af497da96e30a06a63f697a900a
We used the preserved SEEG extraction code, band definitions, first-two-run cohort selection, and independent EDF power audit code.
usesdoi:10.18112/openneuro.ds004100.v1.1.3
Source dataset used for the analyzed SEEG recordings and clinical marks; the cited DOI is for version 1.1.3.
doi:10.3389/fneur.2026.1862336

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3 publications

Public catalog entries on Sciscape.

usesUnder independent, exchangeable patient sampling, the 95 percent interval for late minus early CAR gamma power change rank agreement included zero in 28 SEEG patients
We reused all 64 compact power files, fixed source records, metadata, and audit tools. Its late clinical onset-mark AUC result informed the new early versus late cross-seizure agreement question.
usesBipolar gamma power had mean clinical onset mark AUCs of 0.900 at 0 to 10 seconds and 0.883 at 10 to 20 seconds within named shafts in 26 ds004100 SEEG patients
Its gamma timing result and within-shaft check motivated this distinct primary endpoint. The source cohort is shared.
usesThe gamma timing score gave no clear onset mark AUC gain over power and position in 14 test SEEG patients
We used its 64 unchanged power files, fixed source records, metadata, and two raw examples. Its early and late power comparison helped define the new question.