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q-bio.NC · Neurons and Cognition

Under independent, exchangeable patient sampling, the 95 percent interval for late minus early CAR gamma power change rank agreement included zero in 28 SEEG patients

We compared contact rank agreement across two seizures in 28 SEEG patients. We used public OpenNeuro ds004100, version 1.1.3. The primary signal used a common average reference (CAR) and gamma power change from each seizure's own baseline. Early time was 0 to 4 seconds after the source onset mark. Late time was 16 to 20 seconds. Mean early agreement was 0.3341. Mean late agreement was 0.4435. The equal-patient mean of late minus early agreement was 0.1094. Its 95 percent patient bootstrap interval was -0.0391 to 0.2649. The exact two-sided sign-flip test gave p = 0.1803. Sixteen patients had positive differences; twelve had negative differences. The fixed primary test did not show higher late agreement at the 0.05 level. It did not show equal agreement. Patient inference assumes independence and exchangeable sampling. The sign-flip test also assumes null sign symmetry. Fixed descriptive bipolar and high gamma checks had intervals above zero. Absolute gamma power had higher early agreement than gamma power change in the observed cohort. These checks do not change the primary result. This is a secondary analysis of selected patients, not a test in new patients. The package preserves 64 power inputs, source versions and hashes, all patient results, resampling draws, source checks, code, and repeat instructions.

stereoelectroencephalography · SEEG · epilepsy · gamma power · contact rank agreement · seizure · common average reference

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References

5
  1. usesGamma power change had higher mean clinical onset mark AUC at 16 to 20 seconds than at 0 to 4 seconds in 28 ds004100 SEEG patients with common average reference sci:sha256:4a3728b39032e039126d96e6e620d755355a4e9a05d5473ea4c0b0d047fe5e82

    We reused all 64 compact power files, fixed source records, metadata, and audit tools. Its late clinical onset-mark AUC result informed the new early versus late cross-seizure agreement question.

  2. usesA shared baseline increased early to late gamma change agreement in 28 ds004100 SEEG patients with common average reference sci:sha256:21e1e66e6cd44db34a824ea0b78b1faf0d840807a14a8ed8bea444738d22a74b

    Earlier power inputs, source manifests, and audit tools from this work were preserved through the parent package. Its baseline analysis informed interpretation of absolute power and power change.

  3. usesEarly gamma ranks had higher mean agreement across references than across seizures in 32 ds004100 SEEG patients sci:sha256:4537e0031e79d6302fa623490378be55c0329af497da96e30a06a63f697a900a

    We used the original extraction code and two-seizure source selection preserved through the parent package. They define the signal windows, pair anchors, references, and power measurements.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The publication analyzes compact power inputs derived from OpenNeuro ds004100 version 1.1.3.

  5. doi:10.3389/fneur.2026.1862336

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