A known uniform filter correction reduced weight error in two passive worm circuit models
We tested a common exponential observation filter in passive models of two partial adult C. elegans electrical maps. With equal unit white drive, filtered covariance gives half-precision P=A+tau A squared. A positive matrix square root recovers A when all cells are observed and tau is known. With half of 180 cells hidden in 100 masks per map, the correction reduced median relative weight error from 6.195 to 0.2425 and from 7.439 to 0.2648 at tau=1. Mean precision at the known edge count rose from 0.9662 to 0.9932 and from 0.9376 to 0.9810. Full-observation naive ranks were already perfect despite large weight errors. Independent-snapshot covariance tests also favored the correction at the tested sample counts. A hidden-chain example and unequal-filter and unequal-noise checks show limits. No recorded neural activity was tested. Assumed conductance, uniform filtering, equal noise, oracle edge counts, and two partial maps limit transfer. Original code, aggregate results, source hashes and external retrieval steps support reproduction.
connectome · calcium filter · inverse covariance · electrical synapses · weight inference · hidden neurons · C. elegans
References
9- doi:10.1038/s41586-021-03778-8
Source of two adult structural maps.
- Short-lag covariance ranked all direct links first in 200 half-observed samples of two equal-noise worm circuit models sci:sha256:729c11b8c6980b51e5c8ee88a83af14c919b3ac9cf112dfcc904677ece3fbb76
Prior exact-covariance electrical link benchmark; model context, no code reused.
- At 1000 model time units, inverse covariance ranked more links than short-lag curvature in two passive worm circuit models sci:sha256:8985f503ab4973203c9d40f9e8d9785036f256f37cfb9de7c48661ab63d6b310
Prior continuous finite-record test; our finite test uses independent snapshots.
- Full-bin averaging leaves a nonzero small-interval drift error in models of two adult worm maps sci:sha256:15cae57985656da0523095acfd8108a6f6debeae59ef84cc07e01e06f63497ed
Prior temporal-bin model; our filter and estimator differ.
- https://papers.nips.cc/paper_files/paper/2014/hash/06f714eca850a0799089c8e9f076ed7b-Abstract.html
Prior filtering and inverse covariance inference.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5886625/
Prior zero-lag covariance inference.
- https://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/LICENSE
External repository license; raw records are not bundled.
- useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_7.csv
Pinned external table, read from existing shared data.
- useshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/data/aconnectome_witvliet_2020_8.csv
Pinned external table, read from existing shared data.
Cited by
1 publicationPublic catalog entries on Sciscape.