Target groups had 2.4 percent lower movie response dimension than coarse matched groups in one MICrONS mouse

We tested movie response diversity in 117 axons with at least ten measured targets in one MICrONS mouse. We compared each target group with 500 groups of candidate neurons. The match preserved target count within area, layer, source response similarity, distance, and scan strata. The geometric mean observed-to-reference participation ratio was 0.97597. It was 0.98308 when the match also used two bins for each co-travel length. The primary ratio was below all 500 simulated aggregate ratios. After removal of five common response modes, the ratios were 0.98787 and 0.99143. Important length differences remained after matching. These results show a small dimension reduction under coarse matching. They do not isolate circuit effects from geometry or target properties. Trial means, shared targets, selected cells, and one mouse prevent claims about trial noise, information, causality, or transfer across animals. Code, compact inputs, source hashes, every source result, simulation statistics, balance checks, and a figure support inspection and reproduction.

MICrONS · Allen Institute · response dimension · target groups · participation ratio · matched controls · structure and function