Full movie response dimension of measured input groups was within sampled wiring ranges in one MICrONS mouse

We tested movie response dimension in 169 MICrONS cells with five to twelve measured input partners. We used graphs that preserve both cell degrees, candidate support and coarse edge strata for anatomy, pair response similarity and distance. The geometric mean observed-to-control dimension ratio was 0.98765. The central 95 percent graph control range was 0.98177 to 1.00955. The full-response result did not show a clear reduction under these controls. A second seed, co-travel length bins and removal of five common response modes tested sensitivity. After five modes were removed, ratios of 0.98772 to 0.98856 were below the respective control ranges. This secondary pattern is small and model-dependent. The length-constrained chain had a rough effective sample size of 20 for the full-response statistic. These are simulation ranges, not confidence intervals across animals. Partial input groups, coarse controls, dependent cells and one animal limit the result. Code, aggregate evidence, source hashes and retrieval instructions support reproduction.

MICrONS · input convergence · response dimension · connectome · degree controls · Allen Institute