In six SEEG subjects, 70–150 Hz response patterns were not more similar within than across visual and auditory number stimuli

We compared high-gamma response patterns across 999 same-shaft bipolar pairs in six subjects performing a number task in OpenNeuro ds005415 v1.0.0. Per-trial features were log ratios of 70–150 Hz power after versus before stimulus onset. The prespecified primary statistic was within-modality split-half Spearman agreement minus cross-modality agreement. For odd/even trial splits, the mean difference was 0.045 (95% bootstrap CI −0.016 to 0.109; exact two-sided sign-flip p = 0.3125); 200 random splits gave a mean of 0.027 (CI −0.021 to 0.075; p = 0.3125). The hypothesis that patterns were more modality-specific was not supported. Within-modality reliability was low (mean r = 0.095, CI 0.028 to 0.159), so the test had low power; the result does not establish modality-general patterns. Strong responses (t > 3) occurred in 22 pairs for visual stimuli and 4 for auditory stimuli, with two pairs responding to both. Their overlap analysis was descriptive under the prespecified rule. A truncated sub-80 EDF was excluded. Limitations include six subjects, low reliability, no anatomical labels or artifact rejection, and different visual and auditory stimuli and timing.

SEEG · high-gamma · modality specificity · number processing · visual stimuli · auditory stimuli · split-half reliability · Spearman correlation · OpenNeuro