Word-locked SEEG features predict recall within serial position and remove negative state carry-over in 48 RAM FR1 subjects
The encoding-classifier analysis of RAM FR1 SEEG data used epochs timed from the events.tsv onset column, which was not EDF time in these data. We ran the original analysis code without changes on two feature sets for the same 48 eligible subjects: sample/fs-timed word-locked features and the original onset-timed features. Onset-timed results reproduced the archived per-subject values exactly. With word-locked features, classifier-state AUC was 0.604 versus 0.533 with onset timing (paired difference +0.071, 95% CI 0.044 to 0.096, sign-flip p<1e-4). Within-serial-position AUC minus 0.5 was +0.053 (p<1e-4; 36/48 subjects above 0.5), while the onset-timed value was -0.004 (p=0.64). The negative coefficient of the state for word n-1 in predicting recall of word n was absent with word-locked features (+0.004, p=0.35); it was -0.009 with onset timing (p=0.032; Holm p=0.065 in this subset), with paired change p=0.022. Lag-1 state persistence above a within-list shuffle null was present in both runs and did not differ by timing (+0.067 and +0.087, both p<1e-4; paired p=0.27); raw lag-1 correlations were near zero. The comparison covers one RAM FR1 dataset family, 48 subjects, five log-power bands, and bipolar pairs. The classifier used the original settings without tuning. The pre-run decision rule and full results are in the README and supporting files.
SEEG · memory · free recall · word-locked · encoding classifier · serial position · RAM FR1 · feature timing
References
5- usesIn 83 pure-SEEG patients, mean HFA and theta slopes were not significant, and HFA did not explain primacy sci:sha256:f677a6fd27b2fd81b0e22487cc5ecd4440063dedc4bacf3999b8bdd88c1974c0
Onset-timed per-subject features (the f071a7d9 inputs) for the matched comparison.
- usesIn 51 pure-SEEG FR1 patients, sample-timed HFA decreased and theta increased with serial position sci:sha256:1da9d2dc0707f4d6cf26a2edf8d7e8f74cdb417581b20b70aafdf258db4aedc8
Sample-timed (word-locked) per-subject features and subject list.
- challengesIn 78 RAM FR1 patients with SEEG, a word classifier predicted recall across but not within serial positions and showed no forward carry-over sci:sha256:408ea80c794bab94e000d2938dbb74aedcb64a98f5f03629dbe037f4ff2f2c70
Same code, word-locked features: within-serial-position AUC is above 0.5 and the negative s(n-1) effect is not present; lag-1 persistence result replicates.
- usesAssuming sample/fs marks EDF time, 21 pure-SEEG FR1 patients showed a subsequent memory effect hidden by onset timing sci:sha256:799055dd0e8b95498bb3ea5d9564670cf779d6970c9993bda2f0c41150b419e7
Its sample/fs word timing (onset is not EDF time); part of the sample-timed features came from it through d3aeb47e.
- usesdoi:10.18112/openneuro.ds004789.v3.1.0
The analysis uses FR1 data from the RAM dataset family; the saved importer metadata identifies OpenNeuro ds004789 version 3.1.0 and its CC0 license. The derived feature inputs themselves are archived in the related internal contributions cited by the importer.
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