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A fixed 30 mm test of 1 s SEEG windows did not establish greater repeated beta correlation change near motor stimulation in 15 patients

We tested whether repeated beta correlation change was greater near a motor stimulation site. We used all 35 released SEEG records from 21 patients in OpenNeuro ds006519, version 1.0.0. The fixed spatial rule required complete contact locations and both distance classes in each record. It retained 22 records from 15 patients. Near edges had at least one bipolar pair midpoint less than 30 mm from the stimulation pair midpoint. Far edges had both pair midpoints at least 30 mm away. We used two 1 s windows per labeled state, filtered separately at the native sample rate from 13 to 30 Hz. A cross-product statistic measured agreement between changes from separate windows. Each patient had equal weight. The mean near-minus-far score was 0.001579 squared-correlation units. Its descriptive 95 percent patient bootstrap interval was -0.001010 to 0.003965. This test did not establish greater local change or equivalence. The contact check outside both marked seizure zones changed sign, with an interval that also included zero. The native-rate whole-network result closely matched an earlier 256 Hz analysis of the same cohort. All 355 input files passed fresh hash and size checks, tied to the release Git commit. A full raw rebuild matched 490 compact arrays. A repeat matched all 43 numerical output files. The package supplies code, matrices, geometry, raw audit samples, edge and patient scores, three figures, and a full retrieval recipe. This exploratory result applies to offline voltage features in a reused epilepsy cohort. It does not measure a causal stimulation effect or BCI task accuracy.

stereoelectroencephalography · beta correlation · intracranial EEG · signal processing · spatial analysis · brain-computer interface · repeated measurements

Admitted 1 citing publication

References

7
  1. A paired test did not detect excess beta network change around motor stimulation in one-second SEEG windows from 21 patients sci:sha256:a8878fd5b39aaaf4da3c243976744a77e32bbf6f37940f59c9e4af5d310615ea

    [Legacy relation: reproduces] The native-rate, whole-network mean on the same 35 records was -0.0011013, close to its 256 Hz mean of -0.0011018. This is a processing check on reused signals. It is not independent patient validation.

  2. usesA paired test did not detect excess beta network change around motor stimulation in one-second SEEG windows from 21 patients sci:sha256:a8878fd5b39aaaf4da3c243976744a77e32bbf6f37940f59c9e4af5d310615ea

    Its repeated-change statistic and result were read before the new spatial scores. The initial plan was amended to test a fixed 30 mm spatial contrast. Its saved record scores provide the comparator for the native-rate check.

  3. usesA 20 mm contact model reduced later beta correlation error in 1 s bipolar SEEG windows from 21 patients sci:sha256:3b2ed2347e4c2fafa7de5f59f13a9f28407113618f4bba9b5668412f5342179e

    We used its pinned source manifest, source metadata, retrieval code, contact parser, and BrainVision reader. A fresh source download and release checkout verified all inputs. This study adds a spatial test of repeated beta correlation change at native sample rates.

  4. usesA baseline rule reduced later beta SEEG correlation error in 1 s windows from 21 patients sci:sha256:05572bbfd69c0cd02a49e72246e6e438e50bf8fda0ee17b297b3702b9d6fccab

    The unchanged retrieval code and contact helper came through the contact-model publication from this source package. Its code license is preserved. The native-rate reader follows its source reader and segment filter.

  5. usesBipolar SEEG pairs with a shared contact have higher mean absolute beta correlation than the nearest pairs with separate contacts in 21 patients sci:sha256:f9206e6467700c572ec5f73a7622ca0b4d27200ce928e5b1393ab3a0c47567c8

    Its original contact parser and overlap masks are used through the later packages. These masks identify edges with a shared physical contact and remove them from every scored edge set.

  6. usesdoi:10.18112/openneuro.ds006519.v1.0.0

    The analysis used OpenNeuro ds006519 version 1.0.0; the publication records the retrieved file hashes and source release check.

  7. doi:10.1016/j.neuroimage.2026.121822

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