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Bipolar SEEG pairs with a shared contact have higher mean absolute beta correlation than the nearest pairs with separate contacts in 21 patients

Pairs of bipolar SEEG signals can share one contact. We tested these pairs in all 35 recordings from 21 patients in OpenNeuro ds006519 version 1.0.0. The control pairs had separate contacts and were on the same electrode shaft. Each patient had the same weight. The mean absolute beta correlation contrast was 0.0682. The patient bootstrap 95 percent interval was 0.0305 to 0.1029. The exact two-sided sign-flip test gave p = 0.00256. Eighteen patients had a positive contrast. Removing shared-contact edges changed the top channel at a mean patient rate of 29.3 percent. Random removal of the same number of edges gave 15.8 percent. The imaginary-coherency contrast was 0.0034, with an interval that included zero. Physical distance remains a confound. These results do not prove false edges or a causal stimulation effect. The package supplies event data, network matrices, contact masks, two figures, source hashes, code, and retrieval instructions. A separate full extraction and analysis reproduced the signal arrays, graph arrays, and primary results exactly. A later missing-label correction changed only the seizure-zone sensitivity check. This is an offline benchmark for brain-interface network methods.

bipolar SEEG · contact overlap · beta correlation · intracranial EEG · functional connectivity · brain interfaces · stereoelectroencephalography · imaginary coherency

Admitted 26 citing publications

References

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  1. usesA paired test did not detect increased high-gamma drift in annotated post-stimulation windows from 21 SEEG participants sci:sha256:0eb1cda13cce113a7a1fe70466917eeb0278c662b2155ce27ee9d36ce7636489

    The source audit identified a zero-filled stimulated channel and four conflicting stimulation-frequency fields. We checked these issues against the raw source during final review. The zero-filled channel was already excluded. This audit did not supply our primary endpoint or analysis code.

  2. usesdoi:10.18112/openneuro.ds006519.v1.0.0

    This analysis used the fixed OpenNeuro ds006519 version 1.0.0 source snapshot for its signal and contact data.

  3. doi:10.1016/j.neuroimage.2026.121822
  4. doi:10.1093/braincomms%2Ffcae165
  5. doi:10.1016/j.clinph.2004.04.029

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