A patient permutation test did not detect an outcome group difference in 80 to 150 Hz common average power ranks for treated contacts in 34 selected SEEG patients
We used presurgical high gamma power to rank treated SEEG contacts against unmarked contacts. We tested whether the ranks differed between surgical outcome groups. We used 34 selected patients from public OpenNeuro ds004100 version 1.1.3. Each patient supplied two short interictal sections. Mean patient treatment AUC was 0.524 in 18 patients with successful surgery and 0.536 in 16 patients with recurring seizures. The difference was -0.012. Its patient bootstrap 95 percent interval was -0.167 to 0.140. The two-sided permutation p value was 0.882. The test assumed independent and exchangeable patients under the null. It did not detect a pooled outcome group difference. The wide interval does not show that the groups are equal. Small treatment type groups had opposite mean differences. These planned descriptive estimates need further study. The package contains the analysis plan, source code, clinical label joins, contact scores, patient results, figures, and pinned signal retrieval instructions. Fresh signal calculations matched all 47,856 archived power values.
stereo-EEG · epilepsy surgery · high gamma power · contact ranking · treatment marks · permutation test
References
5- usesReference choice changed high gamma SOZ pair AUCs in 34 ds004100 SEEG participants with 30 second file sections sci:sha256:e85707a636ad0b5863bd24780f3e2d4ce22ef28abad050150ed9dc3d5065b868
We used the CC0 EDF reader and original sample selection, preserved in the power source package. The reader enabled fresh calculations from pinned raw signal sections.
- usesMean seizure onset mark AUC exceeded 0.5 for 80–150 Hz common average power in two selected public SEEG samples sci:sha256:1871772889fd3417669bc22cfc0cc35db83c969a775cc6c3085902b7bbc92c95
We used the full contact power pools, clinical metadata, EDF headers, sample selection, raw range hashes, and source manifest. We joined the contact powers to source treatment marks and surgical outcome labels.
- usesdoi:10.18112/openneuro.ds004100.v1.1.3
The analyzed contact power pools and source metadata came from OpenNeuro ds004100 version 1.1.3.
- doi:10.1093/brain%2Fawab480
Cited for background on normative intracranial EEG maps; it did not supply the new patient results.
- doi:10.1093/brain%2Fawab380
Cited for background on normative interictal intracranial EEG mapping; it did not supply the new patient results.
Cited by
2 publicationsPublic catalog entries on Sciscape.
- usesTreatment coverage of concentrated 80–150 Hz SEEG power gave a small and uncertain Brier gain in 34 patients
Its treated-contact mean-power outcome comparison informed this distinct question about concentration coverage and added patient prediction. We reused no numerical outcome estimates from it.
- usesSix features added to a fixed SOZ model gave a 0.014 mean treated contact AUC gain in 17 SEEG patients with source outcome S
Its prior label audit supplied treatment-token and outcome definitions and known interpretation limits. Its high-gamma estimates are not reused as new results.