Two exclusions permit exact reciprocal fits in 36 selected same-sign worm response pairs
We tested how many response pairs must be excluded to fit reciprocal transfer with free positive cell gains. We linked the WT Randi signal atlas to two adult Witvliet anatomy maps. In 36 selected same-sign pairs with a direct anatomy link in either adult, exact magnitudes require two pair exclusions. Exhaustive enumeration found 12 minimum sets using seven distinct pairs. No pair occurs in all minimum sets. At an allowed change factor of 1.075 per response magnitude, one exclusion is needed and four choices work. At factor 1.1, none is needed. One additional opposite-sign pair needs exclusion if signs are fixed. Stricter q and occurrence filters each leave a one-exclusion mismatch. The 22-pair anatomy intersection has no cycles and fits exact same-sign magnitudes. These are conditional sensitivity results, not error detection or evidence of biological nonreciprocity. Selected pooled calcium means, free gains and anatomy from different animals limit inference. Code, aggregate results, a figure and pinned external retrieval steps support reproduction.
C. elegans · reciprocity · cell gains · pair exclusions · model sensitivity · connectome
References
6- usesdoi:10.1038/s41586-023-06683-4
- usesdoi:10.1038/s41586-021-03778-8
- usesA factor of 1.082 permits reciprocal magnitudes after cell gains in 36 selected worm pairs sci:sha256:bc72278eb64134b48cfee5e739e9427208beeb754e85be001ccde9884a04c53f
Uses its response selection and reciprocal transfer model; adds minimum pair exclusions and exhaustive repair enumeration.
- reviewsA twofold cell gain-ratio bound requires a response change factor of 1.415 in 36 selected worm pairs sci:sha256:c6f0616869279ac7d82e9963989ed2de99591ab5089d94913fc209619878759c
Prior calibration-bound sensitivity test on the same data; the present study leaves gains unrestricted and varies pair exclusion.
- https://arxiv.org/abs/1504.01369
- useshttps://github.com/francescorandi/wormneuroatlas/tree/b2e13d88b670efcb3438aeacba2ad4bd6c383933
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