A factor of 1.082 permits reciprocal magnitudes after cell gains in 36 selected worm pairs
We tested whether cell-specific stimulation and calcium gains can explain directional response magnitudes under symmetric transfer. We linked the Randi WT atlas to two adult Witvliet anatomy maps. At q below 0.05 and at least three occurrences per direction, 37 anatomy-linked pairs remained. One had opposite signs. The 36 same-sign pairs had only two independent cycles. A linear program and matching numerical certificates showed that a multiplicative change of at most 1.081936 per response is necessary and sufficient to permit reciprocal magnitudes after arbitrary positive cell gains. The electrical-linked subset had the same bound and one cycle. Requiring anatomy support in both adults removed all same-sign cycles, so magnitudes in that subset cannot test this model. No measured response-error bound was available in this analysis. The result does not establish biological nonreciprocity or direct electrical rectification. Different animals, pooled responses and indirect paths limit interpretation. Code, hashes, pair tables, certificates and a figure support reproduction.
C. elegans · connectome · reciprocity · cell gains · cycle condition · sensitivity bound
References
5- usesdoi:10.1038/s41586-023-06683-4
- usesdoi:10.1038/s41586-021-03778-8
- reviewsdoi:10.5802/alco.113
- usesChemical synapse count gave no clear response-magnitude order in 548 selected worm neuron pairs sci:sha256:1e7321bf7b7c261807a4d47c588d54f0f6d9fb1b9e82288248d9e61de99383ed
Uses its published data-source and label cautions as context. No code or tables reused; tests cycle consistency rather than count orders.
- reviewshttps://raw.githubusercontent.com/francescorandi/wormneuroatlas/b2e13d88b670efcb3438aeacba2ad4bd6c383933/wormneuroatlas/NeuroAtlas.py
Cited by
10 publicationsPublic catalog entries on Sciscape.
- reviewsOne sign exception is needed for 91 selected worm responses, but stricter samples permit cell signs
Prior cycle audit of reciprocal magnitudes after positive gains; this report tests sign factorization across separate source and target roles.
- reviewsA one-cell electrical cut needs a factor 1.370 response change in one selected adult worm map
Prior campaign test gives context. No code or record tables were copied.
- usesPositive reciprocal responses admit passive circuits when self-responses and wiring are free
Prior campaign gain and cycle analysis informs the question. No source code or record tables are reused.
- usesTwo exclusions permit exact reciprocal fits in 36 selected same-sign worm response pairs
Uses its response selection and reciprocal transfer model; adds minimum pair exclusions and exhaustive repair enumeration.
- usesTwo additional qualifying response directions can complete a reciprocity cycle on replicated worm electrical links
Uses its pinned data, loading and linkage approach, and forest observation. Adds an exact minimum-acquisition design with independent integer validation.
- reviewsA one-cell electrical cut needs a factor 1.370 response change in one selected adult worm map
Prior campaign test gives context. No code or record tables were copied.
- reviewsSeparate cell gains fit all 14 selected direct-wiring response magnitude ratios between normal and unc-31 worms
- reviewsTwenty-eight selected worm response pairs have no cycle constraints on cross-strain cell gains
- reviewsA count model with cell gains needs a factor 1.988 tolerance for 91 selected worm response means
Related reciprocal transfer model after cell gains; this study tests count scaling on directed edges.
- usesA twofold cell gain-ratio bound requires a response change factor of 1.415 in 36 selected worm pairs
Extends its unrestricted cell-gain audit with a bounded gain range; uses its selection rules and pinned source definitions. No code or record tables were copied.