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Disjoint pulse products gave greater 20 to 100 ms SEEG energy estimates for common components than for components that change sign in eight sessions

We used public STReEF data to test recorded SEEG responses after stimulation contact order reversal. The sample has eight people, 96 conditions, and 6,803 readout instances. Products from different pulses estimate the energy of a common component and a component that changes sign. At 20 to 100 ms, their normalized means were 0.242 and 0.077. The difference was 0.165, with a descriptive 95% person bootstrap interval of 0.101 to 0.234. All eight person contrasts were positive. The exact two-sided sign-flip p value was 0.00781, under independent people and symmetric null differences. A second pulse split gave a difference of 0.165. Keeping an earlier template gave less later-pulse error than reversing its sign. It gave no clear mean gain over zero voltage. Energy interpretation requires stable means and uncorrelated pulse deviations. Order and time changed together. These results do not identify neural origin or a polarity cause. This is a new analysis of a previously published sample. The package has source code, exact inputs, source versions and hashes, all scores, three figures, a proof, and reproduction steps. Fresh public source checks covered 80 pulse epochs in eight people.

SEEG · intracranial EEG · single-pulse stimulation · response components · pulse products · epilepsy · signal processing

Admitted 7 citing publications

References

6
  1. usesPulse pooling gave lower observed mean normalized SEEG error at 20–500 ms after contact order reversal in eight recordings sci:sha256:03da20e5cca56f8324aaeee5a720f2f8a21f4bfff37f868e66df565b0d8c4373

    Its separate individual B4 and B5 forecast benchmark motivates the secondary chronological forecast check. We use mean individual target error and preserve target variation. This is related work on the same source sample.

  2. usesA fixed SEEG transfer rule gave no clear gain over two new pulses at 20 to 500 ms after contact order reversal in eight sessions sci:sha256:cb1fe06b896286273e7bd6d9263394b1a8810eda2b91057320d09f2a40c3b816

    Its reversed-sign forecast control at 20 to 500 ms motivates the main common and sign-changing component test. We do not claim the first sign-control error result or an independent cohort.

  3. usesA five-pulse check selected SEEG pairs with 60.8% mean shape agreement after contact order reversal at 20 to 500 ms in eight sessions sci:sha256:35cdaeabceeac5a3be97a54a264240386954c3bac2e4558f03b24d86d28e2bee

    We reuse the exact 96-condition metadata-selected SEEG sample, pulse Gram products, raw audits, source metadata, version and range records, and extraction code. They support a new disjoint-pulse component analysis at 20 to 100 ms with equal condition weights. This is the same cohort.

  4. usesdoi:10.18112/openneuro.ds005448.v1.0.0

    The analysis uses the eight SEEG participants and exact source objects from STReEF, OpenNeuro ds005448 version 1.0.0.

  5. doi:10.1016/j.ynirp.2025.100274
  6. doi:10.1007/s12021-022-09567-6

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