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Local calibration lowered mean pre-onset window alerts from 25.6% to 8.8% for a median monitor in 28 SEEG record pairs after onset shafts were excluded

In 28 matched pairs of SEEG seizure records from patients with epilepsy, a median shaft monitor calibrated in the second record had a lower mean pre-onset alert fraction than a monitor transferred from the first record: 8.8% versus 25.6%, a local-minus-transfer difference of −16.9 percentage points (descriptive patient bootstrap 95% interval −25.6 to −8.9; 20 negative, 3 positive, 5 tied patient differences; exact two-sided sign-test p=0.000488281). During the first 20 seizure seconds, mean alert fractions were 47.1% local and 53.2% transferred (difference −6.1 points; interval −15.0 to 2.5). This exploratory test used one record pair per patient, excluded onset shafts, reused an earlier cohort and methods, and did not establish preservation of seizure detection or a general alert-rate guarantee. It tested seizure-state monitoring, not BCI command accuracy, stimulation benefit, or clinical utility.

SEEG · brain-computer interface · calibration transfer · seizure-state monitoring · signal processing

Admitted 11 citing publications

References

3
  1. usesMedian and maximum monitors had mean AUC 0.763 and 0.774 for the first 20 seizure seconds in 30 SEEG records after onset shafts were excluded sci:sha256:c170342b2e116d03b434dd1a1bf0b84f39fccd140306db39a2b40a7c00ffce27

    We used its median shaft monitor, separate 30-second scale and threshold intervals, and matched first-20-second test. This study adds 28 second records and compares transferred and local fits.

  2. usesPower-ratio deviations exceed early limits more often during seizures outside onset-labeled contact groups in 30 SEEG records sci:sha256:46ab84bca2ba1c6a358b6eaf9312db59b5ed68f3f01bca4eb378539fd4ff1a65

    We reused its 30 SEEG patients, first-record powers, raw audit samples, metadata, EDF extraction code, and frozen source checks. We checked all 280 publication files before analysis.

  3. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    Source data: OpenNeuro ds004100 version 1.1.3; the fixed Git commit and full-file checks are documented in the publication.

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