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An equal patient rate mixture increased five pulse SEEG shape forecast error in eight sessions

We tested probability forecasts for single SEEG responses after electrical stimulation. Public OpenNeuro ds004696 v1.0.1 supplied eight patient sessions, 86 sites, and 430 later pulses. Each site used five early pulses to select one recording pair and form a template. The local forecast was the fraction of early pulses with shape correlation at least 0.8. The comparison gave equal weight to this fraction and the match rate from the other seven patients, assumed to be historical before target use. Mean Brier error was 0.12247 for the local forecast and 0.14361 for the mixture, an increase of 17.3%. Six patients had higher mixture error. A descriptive patient bootstrap gave an error increase of 0.00705 to 0.03931. Mean forecast bias fell by half under equal patient weighting, but probability error increased. These offline results use a previously studied clinical cohort and do not establish performance in new patients or a live interface. The package retains exact pulse products, forecasts, results, figures, source hashes, and reproduction instructions. GPL analysis and extraction scripts are omitted from the SCI payload, so the exact local implementation is unavailable there. Fresh source checks covered two patients.

stereoelectroencephalography · electrical brain stimulation · shape correlation · probability forecast · Brier error · patient transfer · calibration

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References

6
  1. usesPair selection within each fold reduced observed mean normalized error underestimation at 20–500 ms in eight SEEG sessions sci:sha256:cc8dd031a38bd1409ae47b5eded349970f98f6e00038879f4af3c5e34f5c80dc

    This report supplied context on early error estimates and prior cohort use. The current work tests binary shape matches and squared probability error rather than normalized waveform error.

  2. usesA five-pulse check selected more repeatable bipolar SEEG pairs within eight epilepsy patient sessions sci:sha256:b5b7963746f5c6d2a2a8f7844ec590732a4eb152bc7a70979b3bc95c3e27820f

    This work uses the inherited compact data lineage and public derivative retrieval method first preserved here. The license and attribution are retained.

  3. usesIndividual pulse selection gave more later SEEG shape matches than selection by pulse means in eight sessions at r ≥ 0.8 sci:sha256:d10ab8b4c3d6f163e4725cadd1a9d3a48973f8213a028632f0e6408043c51370

    This work uses the exact trial products, chronological pulse map, candidate pairs, and individual-pulse selection module. It adds fixed probability forecasts and Brier error tests.

  4. usesDonor covariance raised mean 16-mode SEEG response AUC after five local fit pulses at 86 selected sites in eight patients sci:sha256:6c4cced9dadb0e1e3eda59b7313983bcc2e732c773a7d1d9a0363f14681fece4

    The donor covariance result motivated the transfer question. The current work tests a scalar patient match-rate mixture and Brier error. Its model and endpoint differ from the cited response detection test.

  5. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analyzed source is OpenNeuro ds004696 version 1.0.1; its version-specific DOI and CC0 license are recorded in the cached source metadata.

  6. doi:10.1523/JNEUROSCI.2201-22.2023

    Source study describing the human limbic system electrical stimulation recordings.

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