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Pair selection within each fold reduced observed mean normalized error underestimation at 20–500 ms in eight SEEG sessions

We tested recording pair selection in five-pulse SEEG calibration. The public data came from OpenNeuro ds004696 version 1.0.1. The primary test used eight patient sessions, 84 stimulation sites, and 884 candidate pairs at 20–500 ms. Each fold tested the same four-pulse mean on its held-out early pulse and five final pulses. Selection with all five early pulses gave mean normalized error underestimation of 0.0846. Selection within each fold gave −0.0051. The reduction was 0.0898, with a descriptive patient interval of [0.0211, 0.1593] and exact patient sign-flip p = 0.0547. The test did not establish a population gain at the 0.05 level. Mean absolute site discrepancy increased from 0.2050 to 0.2557. The voltage-unit analysis also left mean-bias reduction uncertain. Independent score checks, two fresh public-source rebuilds, and complete numerical repeats passed. A simulation confirmed the known independent-pulse risk identity and showed its failure after a later mean change. The package preserves exact inputs, code, source hashes, all fold scores, simulations, figures, and reproduction steps. These reused clinical records test offline calibration, not live interface benefit.

SEEG · cross-validation · error estimation · recording pair selection · brain-computer interface · calibration

Admitted 4 citing publications

References

4
  1. usesA fixed 1.5 factor reduced relative error estimate differences for five-pulse remote SEEG means at 20–500 ms in eight patients sci:sha256:ea314f0cf0b1d18b61f04d53605a2b63e560f1628fda25199c0cc18d30ae31a2

    We used its exact SEEG trial Gram matrices, source metadata, spatial rules, chronological pulse selection, and extraction code. These inputs enabled a new audit of pair selection inside leave-one-out validation with matched four-pulse later errors. We did not use its fixed 1.5 correction factor.

  2. usesA five-pulse shape check selected later repeatable SEEG readouts with 73 percent mean precision in eight patient sessions sci:sha256:12bd1388fbe7a4dcdf818e315987ecdd007064851d53cd5247dc84368ea4642d

    Its early shape selection result supplied context for the recording selection question. Our local plan then tested error estimation after a different maximum M/D pair selection rule. We did not reuse its correlation cutoff.

  3. usesdoi:10.18112/openneuro.ds004696.v1.0.1

    The analysis used source records and derived trial products from this exact OpenNeuro dataset version.

  4. doi:10.1523/JNEUROSCI.2201-22.2023

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