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q-bio.NC · Neurons and Cognition

The 112-second SEEG test did not detect better onset ranking across two records in 36 patients under independence and null sign symmetry

We compared equal 112-second samples within and across two public interictal SEEG records. The fixed low frequency score used 36 patients and 4,252 matched contacts. Mean AUC was 0.6463 within one record and 0.6478 across two records. The mean change was +0.0015 AUC, with a 95 percent patient bootstrap interval of -0.0168 to +0.0184. The paired sign-change test gave p = 0.877. It assumes independent patient effects and sign symmetry under the null. The test did not detect a mean gain and did not prove equal performance. The package preserves the source powers, contact scores, patient results, random draws, code, figures, and pinned signal retrieval records. Direct numerical checks, four fresh signal checks, and a clean offline repeat passed.

SEEG · stereoelectroencephalography · epilepsy · interictal EEG · seizure onset · contact ranking · sampling duration · area under the curve

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References

6
  1. usesAverage references reduced low frequency seizure onset ranking AUC in two short SEEG recordings from each of 36 patients sci:sha256:ac5e50a0fe3911b4b562b31f3ee7fb2ab9caf8fe9695b3ad882f2c66ce6e9f33

    Used all 72 window-power files, the matched contact set, source metadata, and pinned retrieval records. These files enabled the equal duration sampling test. The complete source package is preserved unchanged.

  2. usesA 56-second SEEG threshold test on known contacts did not detect a mean balanced accuracy loss between recordings in 36 patients sci:sha256:a3f941835df4ee7df7dacc6db55762ca1ff0e1be27b6f8d9c99ab9b6b1f1a45e

    Its short-block threshold-transfer result helped define the equal duration control. No fitted threshold was reused.

  3. usesMedian within-file relative gamma rank agreement exceeds between-file agreement at 64 s under common average reference in 36 SEEG patients sci:sha256:780ea4b85d6df76ecf1e0343d99058135d5cdccc23a98ae837195e95d80b5392

    Its duration and record rank-stability results motivated the control for signal duration. No gamma features were reused.

  4. usesdoi:10.18112/openneuro.ds004100.v1.1.3

    The analysis used the public HUP iEEG dataset, release 1.1.3, with saved source hashes and pinned retrieval records.

  5. supportsdoi:10.1038/s41598-019-42347-y

    This study supplies the previously reported low versus delta power association that motivated the fixed score direction; the present analysis is not an exact replication.

  6. doi:10.1093/brain%2Fawad007

    Describes the public HUP intracranial EEG data and discusses transfer of methods in this cohort.

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